中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Current status of studies on Acyl-CoA: Cholesterol Acyltransferase (ACAT) inhibitors

文献类型:期刊论文

作者Din Derong; Shen Jingkang
刊名Chinese Journal New Drugs
出版日期2005
卷号14期号:4页码:396-400
关键词ACAT inhibitor atherosclerosis cholesterol-lowering lipid-lowering
ISSN号1003-3734
其他题名ACAT抑制剂的研究进展
文献子类Review
英文摘要Acyl-CoA: Cholesterol Acyltransferase (ACAT) catalyzes cholesterol esterification, regulates intracellular free cholesterol levels, and promotes both cholesterol absorption in the small in-testine and assembly of low-density lipoprotein (LDL) in the liver. ACAT inhibitors demonstrate cholesterol-lowering and antiatherosclerotic activities by blocking intestinal absorption of dietary cholesterol , inhibiting hepatic secretion of LDL, and preventing the formation of foam cells in the arterial wall. ACAT inhibitors have been regarded as potential lipid-lowering therapies and anti-atherosclerotic therapies. This review presents the current status of ACAT inhibitors in recent years.
WOS研究方向Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:1931433
源URL[http://119.78.100.183/handle/2S10ELR8/268293]  
专题药物化学研究室
作者单位Department of Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China.
推荐引用方式
GB/T 7714
Din Derong,Shen Jingkang. Current status of studies on Acyl-CoA: Cholesterol Acyltransferase (ACAT) inhibitors[J]. Chinese Journal New Drugs,2005,14(4):396-400.
APA Din Derong,&Shen Jingkang.(2005).Current status of studies on Acyl-CoA: Cholesterol Acyltransferase (ACAT) inhibitors.Chinese Journal New Drugs,14(4),396-400.
MLA Din Derong,et al."Current status of studies on Acyl-CoA: Cholesterol Acyltransferase (ACAT) inhibitors".Chinese Journal New Drugs 14.4(2005):396-400.

入库方式: OAI收割

来源:上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。