Synthesis of taxoids against multidrug resistant tumor cells
文献类型：期刊论文
| 作者 | Zhang Shujun2; Shen Jingshan2 ; Wang Jinlan3; Ji Ruyun2; Ando Masayoshi1
|
| 刊名 | Chinese Journal New Drugs
 |
| 出版日期 | 2005 |
| 卷号 | 14期号:5页码:579 |
| 关键词 | taxinine NN-3 taxinine NN-14 laxinine biological activity against multidrug resistant (MDR) taxinine NN-3 laxinine NN-14 |
| ISSN号 | 1003-3734 |
| 其他题名 | MDR逆转活性紫杉烷类化合物的合成 |
| 文献子类 | Article |
| 英文摘要 | Objective:To synthesize taxinine NN-3 and taxinine NN-14 with biological activity against multidrug resistant (MDR) tumor cells. Methods; Starting from taxinine, taxinine NN-3 and taxinine NN-14 were synthesized via selective deacetoxylation ,orthoester and hydrolysis. Results : Total yield of taxinine NN-14 was 68% and taxinine NN-4 was 25% from taxinine. Conclusion: A simple and yielding synthesis of taxinine NN-3 and taxinine NN-14 was achieved. |
| 资助项目 | 中国科学院王宽诚博士后基金[00000000] ; 上海市博士后基金[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2034196 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268294]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Shen Jingshan |
| 作者单位 | 1.Department of Chemistry and Engineering, Niigata University, Niigata 950-2181, Japan. 2.Shangliai Institute of Materiu Medica, Chinese Academy of Sciences, Shanghai 201203, China.; 3.Department of Chemistry and Qiemical Engineering, Qiqihar University, Qiqihar, Heilongjiang 161006, China.; |
| 推荐引用方式 GB/T 7714 | Zhang Shujun,Shen Jingshan,Wang Jinlan,et al. Synthesis of taxoids against multidrug resistant tumor cells[J]. Chinese Journal New Drugs,2005,14(5):579. |
| APA | Zhang Shujun,Shen Jingshan,Wang Jinlan,Ji Ruyun,&Ando Masayoshi.(2005).Synthesis of taxoids against multidrug resistant tumor cells.Chinese Journal New Drugs,14(5),579. |
| MLA | Zhang Shujun,et al."Synthesis of taxoids against multidrug resistant tumor cells".Chinese Journal New Drugs 14.5(2005):579. |
入库方式： OAI收割
来源：上海药物研究所
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