The dual role of adenosine in the cerebral ischemia
文献类型:期刊论文
作者 | Liu Dazhi; Zhu Xingzu |
刊名 | Chinese Bulletin of Life Sciences
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出版日期 | 2005 |
卷号 | 17期号:3页码:227-230 |
关键词 | adenosine adenosine receptor cerebral ischemia neuroprotection neurodestruction |
ISSN号 | 1004-0374 |
其他题名 | 腺苷在脑缺血过程中的双重作用 |
文献子类 | Article |
英文摘要 | The inhibitory neuromodulator adenosine is neuroprotective against damage induced by cerebral ischemia. However, the possible therapeutic value of treating acute cerebral ischemia with systemically admin-istered adenosine is dubious, which is due to several cardiovascular side effects such as bradycardia and hypotension. Except for the cardiovascular side effects, adenosine induces cell death by apoptosis. Here, we reviewed the current understanding about adenosine in cerebral ischemia and raise a number of questions as to the possible mechanisms involved. |
资助项目 | 上海市生命科学重大基础项目[00000000] |
WOS研究方向 | General & Internal Medicine ; Pharmacology & Pharmacy ; Neurosciences & Neurology (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:1966828 |
源URL | [http://119.78.100.183/handle/2S10ELR8/268344] ![]() |
专题 | 药理学第二研究室 |
作者单位 | Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of CAS, Shanghai 201203, China. |
推荐引用方式 GB/T 7714 | Liu Dazhi,Zhu Xingzu. The dual role of adenosine in the cerebral ischemia[J]. Chinese Bulletin of Life Sciences,2005,17(3):227-230. |
APA | Liu Dazhi,&Zhu Xingzu.(2005).The dual role of adenosine in the cerebral ischemia.Chinese Bulletin of Life Sciences,17(3),227-230. |
MLA | Liu Dazhi,et al."The dual role of adenosine in the cerebral ischemia".Chinese Bulletin of Life Sciences 17.3(2005):227-230. |
入库方式: OAI收割
来源:上海药物研究所
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