Molecular Pathway in parkinsons disease: An update on progress
文献类型:期刊论文
作者 | Wang Lizhen; Zhu Xingzu |
刊名 | Chinese Pharmacological Bulletin
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出版日期 | 2004 |
卷号 | 20期号:10页码:1081-1085 |
关键词 | Parkinsons disease oxidative stress dys-function of mitochondrial complex I impairment of ubiquitin-proteasomal system |
ISSN号 | 1001-1978 |
其他题名 | 帕金森病致病的分子研究进展 |
文献子类 | Review |
英文摘要 | Parkinsons disease(PD) is characterized by a selective loss of dopaminergic neurons in the substan-tia nigra pars compacta. The etiology of PD is still not fully understood. Molecular pathways such as oxidative stress, mitochondrial dysfunction and impairment in the ubiquitinproteasomal system, are involved in the process of the dopaminergic neuronal cell death and the progress of PD. The exploration and elucidation of these molecular pathways will provide new potential targets for the drug therapy of PD. |
资助项目 | 上海市生命科学重大基础研究项目[00000000] |
WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:1698082 |
源URL | [http://119.78.100.183/handle/2S10ELR8/268378] ![]() |
专题 | 药理学第二研究室 |
作者单位 | Shanghai Institue of Medical Materia, Shanghai Institutes for Biological Sciences, Chinese Academy of Science, Shanghai 201203, China. |
推荐引用方式 GB/T 7714 | Wang Lizhen,Zhu Xingzu. Molecular Pathway in parkinsons disease: An update on progress[J]. Chinese Pharmacological Bulletin,2004,20(10):1081-1085. |
APA | Wang Lizhen,&Zhu Xingzu.(2004).Molecular Pathway in parkinsons disease: An update on progress.Chinese Pharmacological Bulletin,20(10),1081-1085. |
MLA | Wang Lizhen,et al."Molecular Pathway in parkinsons disease: An update on progress".Chinese Pharmacological Bulletin 20.10(2004):1081-1085. |
入库方式: OAI收割
来源:上海药物研究所
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