Anti-tumour clerodane-type diterpenes from Mitrephora thorelii
文献类型：期刊论文
| 作者 | Meng, Da-Hai1,2; Xu, Yong-Ping1; Chen, Wen-Liang1,2; Zou, Jian1,2; Lou, Li-Guang1 ; Zhao, Wei-Min1
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2007 |
| 卷号 | 9期号:7页码:679-684 |
| 关键词 | Mitrephora thorelii Annonaceae diterpenes anti-tumour activity bioassay-guided isolation |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020601103270 |
| 文献子类 | Article |
| 英文摘要 | Bioassay-guided fractionation of the crude extract of Mitrephora thorelii (Annonaceae) led to the isolation of two clerodane-type diterpenes. Their structures were characterised on the basis of spectroscopic methods as 6 alpha,16,18-trihydroxycleroda-3(4),13(14)-dien-15,16-olide (1) and 16-hydroxycleroda-3(4),13(14)-dien-15,16-olide (2). Compound 1 is a new compound. Compounds 1 and 2 exhibited inhibitory activity against the proliferation of human hepatoma BEL-7402 cells in vitro. Compound 2 also showed an in vivo anti-tumour effect against the growth of hepatoma H22 in mice. |
| WOS关键词 | POLYALTHIA-LONGIFOLIA ; MAINGAYI ; CELEBICA |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000253300400015 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273406]  |
| 专题 | 药理学第一研究室 天然药物化学研究室 |
| 通讯作者 | Zhao, Wei-Min |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Meng, Da-Hai,Xu, Yong-Ping,Chen, Wen-Liang,et al. Anti-tumour clerodane-type diterpenes from Mitrephora thorelii[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2007,9(7):679-684. |
| APA | Meng, Da-Hai,Xu, Yong-Ping,Chen, Wen-Liang,Zou, Jian,Lou, Li-Guang,&Zhao, Wei-Min.(2007).Anti-tumour clerodane-type diterpenes from Mitrephora thorelii.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,9(7),679-684. |
| MLA | Meng, Da-Hai,et al."Anti-tumour clerodane-type diterpenes from Mitrephora thorelii".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 9.7(2007):679-684. |
入库方式： OAI收割
来源：上海药物研究所
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