Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia
文献类型：期刊论文
| 作者 | Chen, Wenliang; Tang, Weidong; Lou, Liguang ; Zhao, Weimin
|
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2006-05 |
| 卷号 | 67期号:10页码:1041-1047 |
| 关键词 | Helicteres angustifolia Sterculiaceae pregnane coumarin triterpenoid cytotoxicity |
| ISSN号 | 0031-9422 |
| DOI | 10.1016/j.phytochem.2006.03.005 |
| 文献子类 | Article |
| 英文摘要 | 2 alpha,7 beta,20 alpha-Trihydroxy-3 beta,21-dimethoxy-5-pregnene (1), 6,7,9 alpha-trihydroxy-3,8, 11 alpha-trimethyleyclohexo-[d,e]-coumarin (2), 3 beta-phy-hydroxy-27-benzoyloxylup-20(29)-en-28-oic acid (3), and 3 beta-hydroxy-27-benzoyloxylup-20(29)-en-28-oic acid methyl ester (4), along with 24 known compounds were isolated and structurally characterized from roots and aerial parts of Helicteres angustifolia (Sterculiaceae). In a preliminary bioassay, the two cucurbitacin derivatives, cucurbitacin D and J exhibited significant inhibitory activities against the growth of both hepatocellular carcinoma BEL-7402 cells and malignant melanoma SK-MEL-28 cells in vitro. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS关键词 | CUCURBITACINS ; SPECTROSCOPY ; GLYCOSIDES ; FRUITS ; ISORA ; ACID |
| WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000238456200015 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273613]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Zhao, Weimin |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Dept Nat Prod Chem, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Wenliang,Tang, Weidong,Lou, Liguang,et al. Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia[J]. PHYTOCHEMISTRY,2006,67(10):1041-1047. |
| APA | Chen, Wenliang,Tang, Weidong,Lou, Liguang,&Zhao, Weimin.(2006).Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia.PHYTOCHEMISTRY,67(10),1041-1047. |
| MLA | Chen, Wenliang,et al."Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia".PHYTOCHEMISTRY 67.10(2006):1041-1047. |
入库方式： OAI收割
来源：上海药物研究所
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