Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis
文献类型：期刊论文
| 作者 | Chang, J; Xu, J; Li, M ; Zhao, M; Ding, J; Zhang, JS
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2005-09 |
| 卷号 | 71期号:9页码:861-866 |
| 关键词 | Salvia prionitis Labiatae diterpenoid prionoids A-F cytotoxic activity |
| ISSN号 | 0032-0943 |
| DOI | 10.1055/s-2005-871279 |
| 文献子类 | Article |
| 英文摘要 | Six novel 4,5-seco-rearranged abietane diterpenoids, including one tetracyclic diterpenoid, prionoid A (1), two tricyclic diterpenoids, prionoids B (2) and C (3), and three dicyclic diterpenoids, prionoids D (4), E (5), and F (6), were isolated from the roots of Salvia prionitis Hance (Labiatae). Their structures were elucidated using spectroscopic analysis. The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination. Moreover, it was found that 4 (IC50 = 0.41 mu M) and 5 (IC50 = 0.72 mu M) showed significant cytotoxic activity against P-388 and A-549 cell lines, respectively. |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
| 语种 | 英语 |
| WOS记录号 | WOS:000232667000012 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273812]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Zhang, JS |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chang, J,Xu, J,Li, M,et al. Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis[J]. PLANTA MEDICA,2005,71(9):861-866. |
| APA | Chang, J,Xu, J,Li, M,Zhao, M,Ding, J,&Zhang, JS.(2005).Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis.PLANTA MEDICA,71(9),861-866. |
| MLA | Chang, J,et al."Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis".PLANTA MEDICA 71.9(2005):861-866. |
入库方式： OAI收割
来源：上海药物研究所
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