A novel bis-furan derivative, two new natural furan derivatives from Rehmannia glutinosa and their bioactivity
文献类型：期刊论文
| 作者 | Li, YS; Chen, ZJ; Zhu, DY |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2005-02 |
| 卷号 | 19期号:2页码:165-170 |
| 关键词 | Rehmannia glutinosa novel bis-furan derivative new natural furan derivatives immunomodulation inhibition of blood platelet aggregation |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786410410001704787 |
| 文献子类 | Article |
| 英文摘要 | A novel bis-furan derivative and two new natural furan derivatives were isolated from the CHCl3 extracts of the dried roots of Rehmannia glutinosa (Gaerth) Lilosch. Their structures were identified as 1,5-bis(5-methoxymethyl)furan-2-yl-penta-1,4-dien-3-one 1, (E)-4-(5-(methoxymethyl)furan-2-yl)but-3-en-2-one 2 and (E)-4(5-(hydroxymethyl)furan-2-yl)but-3-en-2-one 3 on the basis of spectral data. Moreover, biological assay showed that 1 (10 mug/mLmu) and 3 (10 mug/mL) can promote immune activity, 2 (100 mug/mL) and 3 (100 mug/mL) inhibit immune activity and 1 can inhibit blood platelet aggregation. |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000226668800011 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273933]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Li, YS |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, Inst Materia Media, State Key Lab New Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, YS,Chen, ZJ,Zhu, DY. A novel bis-furan derivative, two new natural furan derivatives from Rehmannia glutinosa and their bioactivity[J]. NATURAL PRODUCT RESEARCH,2005,19(2):165-170. |
| APA | Li, YS,Chen, ZJ,&Zhu, DY.(2005).A novel bis-furan derivative, two new natural furan derivatives from Rehmannia glutinosa and their bioactivity.NATURAL PRODUCT RESEARCH,19(2),165-170. |
| MLA | Li, YS,et al."A novel bis-furan derivative, two new natural furan derivatives from Rehmannia glutinosa and their bioactivity".NATURAL PRODUCT RESEARCH 19.2(2005):165-170. |
入库方式： OAI收割
来源：上海药物研究所
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