Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dicatamnus dasycarpus
文献类型：期刊论文
| 作者 | Chang, J; Xuan, LJ ; Xu, YM; Zhang, JS
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2002-05 |
| 卷号 | 68期号:5页码:425-429 |
| 关键词 | Dictamnus dasycarpus Rutaceae dasycarpusides A and B phenolic glycosides cytotoxic activity immunosuppressive activity |
| ISSN号 | 0032-0943 |
| DOI | 10.1055/s-2002-32077 |
| 文献子类 | Article |
| 英文摘要 | Five new compounds, two degraded terpene glycosides, dasycarpusides A and B (1, 2), and three phenolic glycosides, 2-methoxy-4-hydroxymethylphenol 1-O-alpha-rhamnopyranosyl-(1"-->6')-beta-glucopyranoside (3), 2-methoxy-4-acetylphenol 1-o-alpha-rhamnopyranosyl-(1"-->6')-beta-glucopyranoside (4), and 2-methoxy-4-(8-hydroxyethyl)-phenol 1-O-alpha-rhamnopyranosyl-(1"-->6')-beta-glucopyranoside (5), were isolated from the water-soluble constituents of the root bark of Dictamnus dasycarpus Turcz. (Rutaceae). Their structures were elucidated by spectroscopic analysis and chemical evidence. Moreover, it was found that dasycarpuside A (1) showed weak cytotoxic activity against A-549 (human lung adenocarcinoma) cell line, while 4 and 5 showed more remarkable activity of inhibiting the proliferation of T-cells in vitro. |
| WOS关键词 | DICTAMNUS-DASYCARPUS ; SESQUITERPENE |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
| 语种 | 英语 |
| WOS记录号 | WOS:000176221600009 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274366]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Zhang, JS |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chang, J,Xuan, LJ,Xu, YM,et al. Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dicatamnus dasycarpus[J]. PLANTA MEDICA,2002,68(5):425-429. |
| APA | Chang, J,Xuan, LJ,Xu, YM,&Zhang, JS.(2002).Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dicatamnus dasycarpus.PLANTA MEDICA,68(5),425-429. |
| MLA | Chang, J,et al."Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dicatamnus dasycarpus".PLANTA MEDICA 68.5(2002):425-429. |
入库方式： OAI收割
来源：上海药物研究所
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