中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Evaluation of toxicity of some saponins on brine shrimp

文献类型:期刊论文

作者Zhao, WM; Qin, GW; Lou, LG
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
出版日期1999
卷号1期号:4页码:307-311
关键词Artemia salina brine shrimp test bioassay methods saponin cytotoxicity
ISSN号1028-6020
DOI10.1080/10286029908039879
文献子类Article
英文摘要Toxicity of several types of saponins (1-11) against brine shrimp (Artemia salina) were evaluated. As a result, it was found that most tested compounds were not toxic to brine shrimp at high enough concentration. The most toxic saponin (1) to brine shrimp showed also cytotoxicity towards HL-60 tumor cell line using MTT assay. Brine shrimp model may thus be used as benchtop assay in finding cytotoxic components from saponin-containing fractions of plant extracts.
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000088287200009
出版者HARWOOD ACAD PUBL GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/274774]  
专题天然药物化学研究室
通讯作者Zhao, WM
作者单位Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China
推荐引用方式
GB/T 7714
Zhao, WM,Qin, GW,Lou, LG. Evaluation of toxicity of some saponins on brine shrimp[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,1999,1(4):307-311.
APA Zhao, WM,Qin, GW,&Lou, LG.(1999).Evaluation of toxicity of some saponins on brine shrimp.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,1(4),307-311.
MLA Zhao, WM,et al."Evaluation of toxicity of some saponins on brine shrimp".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 1.4(1999):307-311.

入库方式: OAI收割

来源:上海药物研究所

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