Two new humulanolides from the roots of Cynanchum wilfordii
文献类型:期刊论文
作者 | Li, Jin-Long; Fu, Yan; Zhang, Hai-Yan; Zhao, Wei-Min |
刊名 | TETRAHEDRON LETTERS |
出版日期 | 2015-11-18 |
卷号 | 56期号:46页码:6503-6505 |
ISSN号 | 0040-4039 |
关键词 | Humulanolides Cynanchum wilfordii Absolute configuration Acetylcholinesterase inhibitor |
DOI | 10.1016/j.tetlet.2015.10.016 |
文献子类 | Article |
英文摘要 | Wilfolides A (1) and B (2), two rare humulanolides with an unusual bicyclo[6.3.0]undecane core and an adjoining butyrolactone moiety, were isolated from the roots of Cynanchum wilfordii. Their structures were elucidated by spectroscopic analysis, and the absolute configurations were confirmed by X-ray crystallography using Cu K alpha radiation. This is the first Letter of humulanolides from the family Apocynaceae. Compound 1 exhibited weak acetylcholinesterase inhibitory activity. (C) 2015 Elsevier Ltd. All rights reserved. |
WOS关键词 | C-21 STEROIDAL GLYCOSIDES ; DERIVATIVES ; METATHESIS ; CYNANDIONE ; CELLS |
资助项目 | National Natural Science Foundation of China[81273399] |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS记录号 | WOS:000364436300050 |
源URL | [http://119.78.100.183/handle/2S10ELR8/276318] |
专题 | 天然药物化学研究室 |
通讯作者 | Zhao, Wei-Min |
作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Jin-Long,Fu, Yan,Zhang, Hai-Yan,et al. Two new humulanolides from the roots of Cynanchum wilfordii[J]. TETRAHEDRON LETTERS,2015,56(46):6503-6505. |
APA | Li, Jin-Long,Fu, Yan,Zhang, Hai-Yan,&Zhao, Wei-Min.(2015).Two new humulanolides from the roots of Cynanchum wilfordii.TETRAHEDRON LETTERS,56(46),6503-6505. |
MLA | Li, Jin-Long,et al."Two new humulanolides from the roots of Cynanchum wilfordii".TETRAHEDRON LETTERS 56.46(2015):6503-6505. |
入库方式: OAI收割
来源:上海药物研究所
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