The role of the dynorphin/kappa opioid receptor system in anxiety
文献类型:期刊论文
作者 | Hang, Ai2; Wang, Yu-Jun1,3![]() ![]() |
刊名 | ACTA PHARMACOLOGICA SINICA
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出版日期 | 2015-07 |
卷号 | 36期号:7页码:783-790 |
关键词 | dynorphin kappa opioid receptor stress anxiety |
ISSN号 | 1671-4083 |
DOI | 10.1038/aps.2015.32 |
文献子类 | Review |
英文摘要 | Anxiety disorders are the most common and prevalent forms of psychiatric disease, although the biological basis of anxiety is not well understood. The dynorphin/kappa opioid receptor system is widely distributed in the central nervous system and has been shown to play a critical role in modulating mood and emotional behaviors. In the present review, we summarize current literature relating to the role played by the dynorphin/kappa opioid receptor system in anxiety and. opioid receptor antagonists as potential therapeutic agents for the treatment of anxiety disorders. |
WOS关键词 | CORTICOTROPIN-RELEASING-FACTOR ; PRODYNORPHIN MESSENGER-RNA ; NUCLEUS LOCUS-COERULEUS ; KAPPA-OPIATE RECEPTORS ; DORSAL RAPHE NUCLEUS ; FREELY MOVING RATS ; ANXIOLYTIC-LIKE ; PRESYNAPTIC INHIBITION ; SALVIA-DIVINORUM ; PLACE PREFERENCE |
资助项目 | Ministry of Science and Technology of China[2013CB835100] ; National Natural Science Foundation of China[81130087] ; National Natural Science Foundation of China[91232716] ; National Natural Science Foundation of China[81401107] |
WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
CSCD记录号 | CSCD:5474148 |
WOS记录号 | WOS:000357477600002 |
出版者 | ACTA PHARMACOLOGICA SINICA |
源URL | [http://119.78.100.183/handle/2S10ELR8/276479] ![]() |
专题 | 药理学第二研究室 |
通讯作者 | He, Ling |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China; 2.China Pharmaceut Univ, Dept Pharmacol, Nanjing 210009, Peoples R China; 3.Chinese Acad Sci, Collaborat Innovat Ctr Brain Sci, Key Lab Receptor Res, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Hang, Ai,Wang, Yu-Jun,He, Ling,et al. The role of the dynorphin/kappa opioid receptor system in anxiety[J]. ACTA PHARMACOLOGICA SINICA,2015,36(7):783-790. |
APA | Hang, Ai,Wang, Yu-Jun,He, Ling,&Liu, Jing-Gen.(2015).The role of the dynorphin/kappa opioid receptor system in anxiety.ACTA PHARMACOLOGICA SINICA,36(7),783-790. |
MLA | Hang, Ai,et al."The role of the dynorphin/kappa opioid receptor system in anxiety".ACTA PHARMACOLOGICA SINICA 36.7(2015):783-790. |
入库方式: OAI收割
来源:上海药物研究所
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