H-1, C-13 and N-15 backbone and side-chain resonance assignments of the N-terminal ubiquitin-binding domains of the human deubiquitinase Usp28
文献类型：期刊论文
| 作者 | Wen, Yi2; Cui, Rong1,2; Zhang, Huaqun2; Zhang, Naixia2
|
| 刊名 | BIOMOLECULAR NMR ASSIGNMENTS
 |
| 出版日期 | 2014-10 |
| 卷号 | 8期号:2页码:251-254 |
| 关键词 | Deubiquitinase Usp28 Ubiquitin-binding domains Cancer-associated pathways NMR |
| ISSN号 | 1874-2718 |
| DOI | 10.1007/s12104-013-9494-2 |
| 文献子类 | Article |
| 英文摘要 | Deubiquitinases (DUBs) reversibly remove ubiquitin tags from polypeptides and play crucial regulatory roles in multiple cellular processes. Ubiquitin-specific protease 28 (Usp28), a member of the DUB family, exerts its deubiquitination function on key protein molecules in a couple of cancer-associated pathways, likely acting as an oncogenic factor in vivo. The N-terminal ubiquitin-binding domains (UBDs) of Usp28 are potentially required for the full catalytic capacity of Usp28 toward ubiquitin chains. Here we report the expression, purification and H-1, C-13 and N-15 backbone and side-chain resonance assignments of the N-terminal UBDs of Usp28. The BMRB accession number is 19077. |
| WOS关键词 | DNA-DAMAGE-RESPONSE ; EMERGING ROLES ; ENZYMES ; CANCER ; STABILITY ; SYSTEM |
| 资助项目 | National Key Basic Research Program of China[2013CB910900] ; Chinese Academy of Sciences[00000000] |
| WOS研究方向 | Biophysics ; Spectroscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000342080900007 |
| 出版者 | SPRINGER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276888]  |
| 专题 | 分析化学研究室 |
| 通讯作者 | Zhang, Naixia |
| 作者单位 | 1.Nanchang Univ, Coll Med, Nanchang 330031, Jiangxi, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Analyt Chem, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wen, Yi,Cui, Rong,Zhang, Huaqun,et al. H-1, C-13 and N-15 backbone and side-chain resonance assignments of the N-terminal ubiquitin-binding domains of the human deubiquitinase Usp28[J]. BIOMOLECULAR NMR ASSIGNMENTS,2014,8(2):251-254. |
| APA | Wen, Yi,Cui, Rong,Zhang, Huaqun,&Zhang, Naixia.(2014).H-1, C-13 and N-15 backbone and side-chain resonance assignments of the N-terminal ubiquitin-binding domains of the human deubiquitinase Usp28.BIOMOLECULAR NMR ASSIGNMENTS,8(2),251-254. |
| MLA | Wen, Yi,et al."H-1, C-13 and N-15 backbone and side-chain resonance assignments of the N-terminal ubiquitin-binding domains of the human deubiquitinase Usp28".BIOMOLECULAR NMR ASSIGNMENTS 8.2(2014):251-254. |
入库方式： OAI收割
来源：上海药物研究所
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