Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)(2)-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines
文献类型：期刊论文
| 作者 | Yang, Wei1; Huang, Liliang1; Liu, Hong1 ; Wang, Wei1,2,3,4; Li, Hao1,2,3
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| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2013 |
| 卷号 | 49期号:41页码:4667-4669 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c3cc42216j |
| 文献子类 | Article |
| 英文摘要 | We describe an unprecedented Pd(OCOCF3)(2)-catalyzed cascade process for the synthesis of highly functionalized 1,2,3,5-tetra-substituted pyrroles with high efficiency. Unlike documented methods relying on preformed enamines and active halogenated terminal alkenes, the process employs simple 2-alkenal-dicarbonyls and primary amines in 'one-pot'. |
| WOS关键词 | ASYMMETRIC HYDROAMINATION ; CATALYZED HYDROAMINATION ; DERIVATIVES ; ALKENES ; ALKYNES ; HETEROCYCLES ; CYCLIZATION ; CHEMISTRY ; ALCOHOLS ; IMINES |
| 资助项目 | Shanghai Pujiang Program[11PJ1411900] ; East China University of Science & Technology, The Shanghai Committee of Science and Technology[11DZ2260600] ; China 111 Project[B07023] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000318028500025 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277794]  |
| 专题 | 药理学第二研究室 |
| 通讯作者 | Wang, Wei |
| 作者单位 | 1.Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China; 3.E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China; 4.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA |
| 推荐引用方式 GB/T 7714 | Yang, Wei,Huang, Liliang,Liu, Hong,et al. Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)(2)-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines[J]. CHEMICAL COMMUNICATIONS,2013,49(41):4667-4669. |
| APA | Yang, Wei,Huang, Liliang,Liu, Hong,Wang, Wei,&Li, Hao.(2013).Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)(2)-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines.CHEMICAL COMMUNICATIONS,49(41),4667-4669. |
| MLA | Yang, Wei,et al."Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)(2)-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines".CHEMICAL COMMUNICATIONS 49.41(2013):4667-4669. |
入库方式： OAI收割
来源：上海药物研究所
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