中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum

文献类型:期刊论文

作者Wang, Xiao-Ling1; Liu, Bing-Rui2; Chen, Chien-Kuang4; Qin, Guo-Wei3; Lee, Shoei-Sheng4
刊名FITOTERAPIA
出版日期2013-01
卷号84页码:54-57
关键词Sinoscrewtine Injurious effects against H2O2/A beta(25-35) induced oxidative injury DPPH radical scavenging activity Sinomenium acutum
ISSN号0367-326X
DOI10.1016/j.fitote.2012.10.013
文献子类Article
英文摘要An alkaloid with novel skeleton, sinoscrewtine (1), has been isolated from the roots of Sinomenium acutum. Its structure was established by spectral analysis and X-ray crystallographic study, and its possible biosynthetic pathway was delivered. In vitro experiments, 1 showed weak injurious effects against H2O2/A beta(25-35) induced oxidative injury in PC-12 cells and DPPH radical scavenging activity with IC50 of 32.6 mu M. (c) 2012 Elsevier B.V. All rights reserved.
WOS关键词MORPHINANE ALKALOIDS ; HUPERZINE ; INJURY
资助项目Shaanxi Science and Technology Commission[2010JM2014] ; Shaanxi Education Commission[11JS009]
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000316531400009
出版者ELSEVIER SCIENCE BV
源URL[http://119.78.100.183/handle/2S10ELR8/277800]  
专题天然药物化学研究室
通讯作者Wang, Xiao-Ling
作者单位1.Baoji Univ Arts & Sci, Key Lab Phytochem Shaanxi Prov, Baoji 721013, Peoples R China;
2.Northwest Agr & Forest Univ, Coll Sci, Yangling 712100, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
4.Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 100, Taiwan
推荐引用方式
GB/T 7714
Wang, Xiao-Ling,Liu, Bing-Rui,Chen, Chien-Kuang,et al. Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum[J]. FITOTERAPIA,2013,84:54-57.
APA Wang, Xiao-Ling,Liu, Bing-Rui,Chen, Chien-Kuang,Qin, Guo-Wei,&Lee, Shoei-Sheng.(2013).Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum.FITOTERAPIA,84,54-57.
MLA Wang, Xiao-Ling,et al."Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum".FITOTERAPIA 84(2013):54-57.

入库方式: OAI收割

来源:上海药物研究所

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