Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum
文献类型:期刊论文
作者 | Wang, Xiao-Ling1; Liu, Bing-Rui2; Chen, Chien-Kuang4; Qin, Guo-Wei3; Lee, Shoei-Sheng4 |
刊名 | FITOTERAPIA
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出版日期 | 2013-01 |
卷号 | 84页码:54-57 |
关键词 | Sinoscrewtine Injurious effects against H2O2/A beta(25-35) induced oxidative injury DPPH radical scavenging activity Sinomenium acutum |
ISSN号 | 0367-326X |
DOI | 10.1016/j.fitote.2012.10.013 |
文献子类 | Article |
英文摘要 | An alkaloid with novel skeleton, sinoscrewtine (1), has been isolated from the roots of Sinomenium acutum. Its structure was established by spectral analysis and X-ray crystallographic study, and its possible biosynthetic pathway was delivered. In vitro experiments, 1 showed weak injurious effects against H2O2/A beta(25-35) induced oxidative injury in PC-12 cells and DPPH radical scavenging activity with IC50 of 32.6 mu M. (c) 2012 Elsevier B.V. All rights reserved. |
WOS关键词 | MORPHINANE ALKALOIDS ; HUPERZINE ; INJURY |
资助项目 | Shaanxi Science and Technology Commission[2010JM2014] ; Shaanxi Education Commission[11JS009] |
WOS研究方向 | Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000316531400009 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://119.78.100.183/handle/2S10ELR8/277800] ![]() |
专题 | 天然药物化学研究室 |
通讯作者 | Wang, Xiao-Ling |
作者单位 | 1.Baoji Univ Arts & Sci, Key Lab Phytochem Shaanxi Prov, Baoji 721013, Peoples R China; 2.Northwest Agr & Forest Univ, Coll Sci, Yangling 712100, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 4.Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 100, Taiwan |
推荐引用方式 GB/T 7714 | Wang, Xiao-Ling,Liu, Bing-Rui,Chen, Chien-Kuang,et al. Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum[J]. FITOTERAPIA,2013,84:54-57. |
APA | Wang, Xiao-Ling,Liu, Bing-Rui,Chen, Chien-Kuang,Qin, Guo-Wei,&Lee, Shoei-Sheng.(2013).Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum.FITOTERAPIA,84,54-57. |
MLA | Wang, Xiao-Ling,et al."Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum".FITOTERAPIA 84(2013):54-57. |
入库方式: OAI收割
来源:上海药物研究所
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