"One-Pot" Access to 4H-Chromenes with Formation of a Chiral Quaternary Stereogenic Center by a Highly Enantioselective Iminium-allenamine Involved Oxa-Michael-Aldol Cascade
文献类型：期刊论文
| 作者 | Liu, Chunliang2,3; Zhang, Xinshuai2; Wang, Rui3; Wang, Wei1,2 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2010-11-05 |
| 卷号 | 12期号:21页码:4948-4951 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol102096s |
| 文献子类 | Article |
| 英文摘要 | An unprecedented organocatalytic highly enantioselective cascade Michael aldol reaction has been developed in high yields under mild reaction conditions. The "one-pot" process affords an efficient approach to the synthetically and biologically important chiral 4H-chromenes bearing a quaternary stereogenic center. The study significantly expands the scope of less explored organocatalytic iminium-allenamine chemistry. |
| WOS关键词 | ASYMMETRIC-SYNTHESIS ; CONSTRUCTION ; STEREOCENTERS ; ALDEHYDES ; ORGANOCATALYSTS ; BENZOPYRANS ; CATALYSIS ; ETHERS ; ACID |
| 资助项目 | National Natural Science Foundation of China[20932003] ; National Natural Science Foundation of China[90813012] ; National S&T Major Project of China[2009ZX09503-017] ; NSF[Chem-0704015] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000283531000062 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278723]  |
| 专题 | 药理学第二研究室 |
| 通讯作者 | Wang, Rui |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 20203, Peoples R China 2.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA; 3.Lanzhou Univ, State Key Lab Appl Organ Chem, Inst Biochem & Mol Biol, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Liu, Chunliang,Zhang, Xinshuai,Wang, Rui,et al. "One-Pot" Access to 4H-Chromenes with Formation of a Chiral Quaternary Stereogenic Center by a Highly Enantioselective Iminium-allenamine Involved Oxa-Michael-Aldol Cascade[J]. ORGANIC LETTERS,2010,12(21):4948-4951. |
| APA | Liu, Chunliang,Zhang, Xinshuai,Wang, Rui,&Wang, Wei.(2010)."One-Pot" Access to 4H-Chromenes with Formation of a Chiral Quaternary Stereogenic Center by a Highly Enantioselective Iminium-allenamine Involved Oxa-Michael-Aldol Cascade.ORGANIC LETTERS,12(21),4948-4951. |
| MLA | Liu, Chunliang,et al.""One-Pot" Access to 4H-Chromenes with Formation of a Chiral Quaternary Stereogenic Center by a Highly Enantioselective Iminium-allenamine Involved Oxa-Michael-Aldol Cascade".ORGANIC LETTERS 12.21(2010):4948-4951. |
入库方式： OAI收割
来源：上海药物研究所
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