Lycopodium alkaloids from Huperzia serrata
文献类型：期刊论文
| 作者 | Yang, Yan-Fang1; Qu, Shi-Jin1 ; Xiao, Kai2; Jiang, Shan-Hao1; Tan, Jun-Jie1; Tan, Chang-Heng1; Zhu, Da-Yuan1
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2010 |
| 卷号 | 12期号:11页码:1005-1009 |
| 关键词 | Huperzia serrata Lycopodium alkaloids 6-hydroxy-5 15-oxide-lycopodane 12-deoxyhuperzine O [3H]MK-801 binding NMDA receptor |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020.2010.522180 |
| 文献子类 | Article |
| 英文摘要 | A new lycopodane-type Lycopodium alkaloid, 6-hydroxy-5,15-oxide-lycopodane (1), and seven known alkaloids were isolated from the whole plants of Huperzia serrata. Their structures were elucidated by means of spectroscopic methods. 12-Deoxyhuperzine O (2) was reported as a naturally occurring alkaloid for the first time, and showed an antagonist effect on the N-methyl-d-aspartate receptor with an IC50 value of 0.92M. |
| 资助项目 | Ministry of Science and Technology of China[2008ZXJ09002-011] ; Ministry of Science and Technology of China[2009ZX09301-001] |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000284003600012 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279037]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Tan, Chang-Heng |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Nat Med Chem, Shanghai 201203, Peoples R China; 2.Second Mil Med Univ, Fac Naval Med, Lab Toxicol & Pharmacol, Shanghai 200433, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Yan-Fang,Qu, Shi-Jin,Xiao, Kai,et al. Lycopodium alkaloids from Huperzia serrata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2010,12(11):1005-1009. |
| APA | Yang, Yan-Fang.,Qu, Shi-Jin.,Xiao, Kai.,Jiang, Shan-Hao.,Tan, Jun-Jie.,...&Zhu, Da-Yuan.(2010).Lycopodium alkaloids from Huperzia serrata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,12(11),1005-1009. |
| MLA | Yang, Yan-Fang,et al."Lycopodium alkaloids from Huperzia serrata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 12.11(2010):1005-1009. |
入库方式： OAI收割
来源：上海药物研究所
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