Synthesis, characterisation and antitumour activities of gallic acid hydrazone and its rare earth complexes
文献类型：期刊论文
| 作者 | Zhang, Ling1; Zhang, Jian-Hui1; Zhu, Da-yuan2 |
| 刊名 | JOURNAL OF CHEMICAL RESEARCH-S
 |
| 出版日期 | 2008-11 |
| 期号 | 11页码:630-632 |
| 关键词 | synthesis hydrazone rare earths complexes antitumour activity |
| ISSN号 | 0308-2342 |
| DOI | 10.3184/030823408X371326 |
| 文献子类 | Article |
| 英文摘要 | A new gallic acid hydrazone, 3,4,5-trihydroxybenzoyl salicylaldehyde hydrazone, and its four rare earth complexes, [LnL (OAc)(2)] center dot H(2)O (Ln = La(3+), SM(3+), Tb(3+), Dy(3+)), have been synthesised and characterised on the basis of elemental analyses, molar conductivity, IR and (1)H NMR spectra. The antitumour activities of the prepared compounds have also been evaluated. The results indicate that Gallic acid hydrazone and its four complexes synthesised possess antitumour activity to some extent, and the four complexes show higher antitumour activity against the human leukaemia cell line HL-60 than the ligand. The antitumour activity of the gallic acid hydrazone can be improved by the formation of the rare earth complexes. |
| WOS关键词 | ANTIOXIDATIVE ACTIVITY ; COORDINATION COMPOUNDS ; DERIVATIVES |
| 资助项目 | Education Committee Foundation of Shanghai[2006AZ060] ; Education Committee Foundation of Shanghai[37-0111-07-015] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000261732700007 |
| 出版者 | SCIENCE REVIEWS 2000 LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279454]  |
| 专题 | 天然药物化学研究室 |
| 通讯作者 | Zhang, Ling |
| 作者单位 | 1.Shanghai Univ, Coll Environm & Chem Engn, Shanghai 201800, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ling,Zhang, Jian-Hui,Zhu, Da-yuan. Synthesis, characterisation and antitumour activities of gallic acid hydrazone and its rare earth complexes[J]. JOURNAL OF CHEMICAL RESEARCH-S,2008(11):630-632. |
| APA | Zhang, Ling,Zhang, Jian-Hui,&Zhu, Da-yuan.(2008).Synthesis, characterisation and antitumour activities of gallic acid hydrazone and its rare earth complexes.JOURNAL OF CHEMICAL RESEARCH-S(11),630-632. |
| MLA | Zhang, Ling,et al."Synthesis, characterisation and antitumour activities of gallic acid hydrazone and its rare earth complexes".JOURNAL OF CHEMICAL RESEARCH-S .11(2008):630-632. |
入库方式： OAI收割
来源：上海药物研究所
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