Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference
文献类型：期刊论文
| 作者 | Wu, Xue-Qing4; Zan, Gui-Ying2,3; Ju, Yun-Yue4; Chen, Tian-Zhen4; Guo, Liu-Bin2,3; Jiao, Dong-Liang1; Jiang, Hai-Feng4; Deng, Ying-Zhi2,3; Liu, Jing-Gen2,3 ; Zhao, Min4,5
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| 刊名 | BEHAVIOURAL BRAIN RESEARCH
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| 出版日期 | 2018-11-01 |
| 卷号 | 353页码:129-136 |
| 关键词 | Methamphetamine rTMS CPP Dorsolateral striatum GABA(B)R1 |
| ISSN号 | 0166-4328 |
| DOI | 10.1016/j.bbr.2018.07.004 |
| 文献子类 | Article |
| 英文摘要 | The abuse of amphetamine-type stimulants (ATS) has become a global public health issue in recent years, these new-type drugs can cause addiction and serious cognitive impairment. However, there are no effective methods for the prevention and treatment of ATS addiction at present. Repetitive transcranial magnetic stimulation (rTMS) is a painless and non-invasive new therapeutic approach that has been used for the treatment of depression and other neuropsychiatric disorders, but whether it can be used to treat drug addiction is unclear. In the present study, we investigated the possible effects of rTMS on methamphetamine(METH)-induced conditioned place preference (CPP). High-frequency (10 Hz) and low-frequency stimulation patterns (1 Hz) were applied to test the effect of rTMS on METH -induced CPP. The results showed that low-frequency but not high frequency rTMS could block METH-CPP, accompanied with a downregulation of gamma-aminobutyric acid type B receptor subunit 1 (GABA(B)R1) expression in rat dorsolateral striatum. These results suggested that low-frequency rTMS could effectively inhibit the development of METH addiction and shed light on the rTMS as a potential approach for the prevention of drug addiction. |
| WOS关键词 | DORSOLATERAL PREFRONTAL CORTEX ; LONG-TERM POTENTIATION ; GABA(B) RECEPTOR ; PRESYNAPTIC INHIBITION ; SYNAPTIC PLASTICITY ; DOPAMINE NEURONS ; DRUG-ADDICTION ; USE DISORDERS ; ANIMAL-MODEL ; EXPRESSION |
| 资助项目 | National Nature Science Foundation of China[U1502228] ; National Nature Science Foundation of China[81771436] ; Program of Shanghai Academic Research Leader[17XD1403300] ; Shanghai Municipal Health and Family Planning Commission[2017ZZ02021] ; Shanghai Key Laboratory of Psychotic Disorders[13DZ2260500] |
| WOS研究方向 | Behavioral Sciences ; Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:000442333200016 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279525]  |
| 专题 | 药理学第二研究室 |
| 通讯作者 | Liu, Jing-Gen; Zhao, Min |
| 作者单位 | 1.Bengbu Med Coll, Bengbu, Anhui, Peoples R China; 2.Chinese Acad Sci, Collaborat Innovat Ctr Brain Sci, Shanghai 201203, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China; 4.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Collaborat Innovat Ctr Brain Sci, Shanghai, Peoples R China; 5.Shanghai Key Lab Psychot Disorders, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Xue-Qing,Zan, Gui-Ying,Ju, Yun-Yue,et al. Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference[J]. BEHAVIOURAL BRAIN RESEARCH,2018,353:129-136. |
| APA | Wu, Xue-Qing.,Zan, Gui-Ying.,Ju, Yun-Yue.,Chen, Tian-Zhen.,Guo, Liu-Bin.,...&Zhao, Min.(2018).Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference.BEHAVIOURAL BRAIN RESEARCH,353,129-136. |
| MLA | Wu, Xue-Qing,et al."Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference".BEHAVIOURAL BRAIN RESEARCH 353(2018):129-136. |
入库方式： OAI收割
来源：上海药物研究所
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