Isolation and identification of two new epimer from the mother liquid of megestrol acetate
文献类型：期刊论文
| 作者 | Yang Zhongduo2; Chen Hua2; Wang Youfu1; Lin Libo1; Li Yuanchao2 |
| 刊名 | Acta Pharmaceutica Sinica
 |
| 出版日期 | 2005 |
| 卷号 | 40期号:9页码:830-833 |
| 关键词 | Megestrol acetate 17alpha-acetoxy-2beta,6alpha-dimethylprega-4-ene-3,20-dione 17alpha-acetoxy-2alpha, 6alpha-dimethylprega-4-ene-3,20-dione |
| ISSN号 | 0513-4870 |
| 其他题名 | 安宫黄体酮母液中两个新化合物的分离与结构鉴定 |
| 文献子类 | Article |
| 英文摘要 | Aim To study the impurity in the drug megestrol acetate. Methods Chromatography methods were used to separate the chemical constituents. Their structures were determined by NMR and MS spectral analysis. Results Two new epimers were isolated from the mother liquid of the drug megestrol acetate. Conclusion These new epimers were identified as 17alpha-acetoxy-2beta,6alpha-dimethylprega-4-ene-3,20-dione （ 1 ） and 17alpha-acetoxy-2alpha, 6alpha-dimethylprega-4-ene-3,20-dione （ 2 ）. |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2166585 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268358]  |
| 专题 | 药物化学研究室 |
| 作者单位 | 1.Zhejiang Xianju Zhiyao Erchang, Zhejiang 317300, China. 2.Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.; |
| 推荐引用方式 GB/T 7714 | Yang Zhongduo,Chen Hua,Wang Youfu,et al. Isolation and identification of two new epimer from the mother liquid of megestrol acetate[J]. Acta Pharmaceutica Sinica,2005,40(9):830-833. |
| APA | Yang Zhongduo,Chen Hua,Wang Youfu,Lin Libo,&Li Yuanchao.(2005).Isolation and identification of two new epimer from the mother liquid of megestrol acetate.Acta Pharmaceutica Sinica,40(9),830-833. |
| MLA | Yang Zhongduo,et al."Isolation and identification of two new epimer from the mother liquid of megestrol acetate".Acta Pharmaceutica Sinica 40.9(2005):830-833. |
入库方式： OAI收割
来源：上海药物研究所
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