Progress in characterization of novel lysine acyl modifications
文献类型:期刊论文
作者 | Tan Minjia![]() |
刊名 | Chinese Bulletin of Life Sciences
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出版日期 | 2018 |
卷号 | 30期号:4页码:455-461 |
关键词 | succinylation crotonylation malonylation glutarylation 2-hydroxyisobutyrylation beta-hydroxybutyrylation |
ISSN号 | 1004-0374 |
其他题名 | 组蛋白赖氨酸酰化新修饰研究进展 |
文献子类 | Review |
英文摘要 | Protein post-translational modifications (PTMs) play fundamental and diverse biological functions in cells, such as cell growth, differentiation and metabolism. Lysine acyl modifications are an important class of PTMs, which is widely involved in cell differentiation, energy metabolism and other important physiological activities. In recent years, due to the development of high sensitive and high resolution mass spectrometry-based proteomics technologies, many novel lysine acyl modifications with unique biological functions have been discovered. This review summarized the recent advances of the identification of novel lysine acyl modifications (including succinylation, crotonylation, malonylation, glutarylation, 2-hydroxyisobutyrylation, beta-hydroxybutyrylation), their regulatory enzymes, substrates, and roles in physiology and pathology. |
资助项目 | 国家自然科学基金项目[00000000] |
WOS研究方向 | Biotechnology & Applied Microbiology (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:6251277 |
源URL | [http://119.78.100.183/handle/2S10ELR8/269171] ![]() |
专题 | 化学蛋白质组学研究中心 |
通讯作者 | Tan Minjia |
作者单位 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, The State Key Laboratory of Drug Research, Shanghai 201203, China. |
推荐引用方式 GB/T 7714 | Tan Minjia,Zhu Mingrui. Progress in characterization of novel lysine acyl modifications[J]. Chinese Bulletin of Life Sciences,2018,30(4):455-461. |
APA | Tan Minjia,&Zhu Mingrui.(2018).Progress in characterization of novel lysine acyl modifications.Chinese Bulletin of Life Sciences,30(4),455-461. |
MLA | Tan Minjia,et al."Progress in characterization of novel lysine acyl modifications".Chinese Bulletin of Life Sciences 30.4(2018):455-461. |
入库方式: OAI收割
来源:上海药物研究所
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