Recent research progress in small molecule AMPK direct activators
文献类型：期刊论文
| 作者 | Wei Qiangqiang2; Duan Wenhu1 ; Zhou Jinpei2; Zhang Huibin2
|
| 刊名 | Journal of China Pharmaceutical University
 |
| 出版日期 | 2015 |
| 卷号 | 46期号:4页码:406-415 |
| 关键词 | AMP-activated protein kinase AMPK direct activators structure-activity relationship type 2 diabetes new target advances |
| ISSN号 | 1000-5048 |
| 其他题名 | 小分子AMPK直接激动剂的最新研究进展 |
| 文献子类 | Review |
| 英文摘要 | Type 2 diabetes,an epidemic disorder characterized by high blood glucose level associated with microvascular complications,is one of the main causes of human suffer across the globe,with no effective medicine up to now.AMP-activated protein kinase(AMPK),a highly conserved serine/threonine protein kinase,is a key sensor and regulator of intracellular and whole-body energy metabolism.Small molecule AMPK direct activators have been proven to lower blood-glucose,which is a promising candidate for the treatment of type 2 diabetes.The progress on the research of small molecule AMPK direct activators in recent years is summarized in this paper. |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:5471872 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269277]  |
| 专题 | 药物化学研究室 |
| 作者单位 | 1.Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China. 2.Center of New Drug Research, China Pharmaceutical University, Nanjing, Jiangsu 210009, China.; |
| 推荐引用方式 GB/T 7714 | Wei Qiangqiang,Duan Wenhu,Zhou Jinpei,et al. Recent research progress in small molecule AMPK direct activators[J]. Journal of China Pharmaceutical University,2015,46(4):406-415. |
| APA | Wei Qiangqiang,Duan Wenhu,Zhou Jinpei,&Zhang Huibin.(2015).Recent research progress in small molecule AMPK direct activators.Journal of China Pharmaceutical University,46(4),406-415. |
| MLA | Wei Qiangqiang,et al."Recent research progress in small molecule AMPK direct activators".Journal of China Pharmaceutical University 46.4(2015):406-415. |
入库方式： OAI收割
来源：上海药物研究所
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