Small molecules targeting Staphylococcus aureus virulence
文献类型：期刊论文
| 作者 | Chen Feifei; Di Hongxia; Lan Lefu
|
| 刊名 | Chinese Science Bulletin
 |
| 出版日期 | 2013 |
| 卷号 | 58期号:36页码:3743-3752 |
| 关键词 | Staphylococcus aureus antibiotic resistant virulence factors small molecule inhibitors |
| ISSN号 | 0023-074X |
| 其他题名 | 金黄色葡萄球菌重要毒力因子的功能及其抑制剂研究进展 |
| 文献子类 | Review |
| 英文摘要 | Staphylococcus aureus causes a variety of infections in humans, ranging from minor skin and wound infections to life-threatening diseases. The increasing prevalence of bacterial strains involving so-called superbugs such as MRSA (Methicillin-resistant Staphylococcus aureus) demands the discovery of new drugs. Targeting bacterial virulence rather than bacterial growth represents a new paradigm to antimicrobial therapy that offers promising opportunities to prevent and treat infectious diseases. Here, we review recent research progress in the identification of attractive targets for new anti-virulence drugs against Staphylococcus aureus and small molecules that block Staphylococcus aureus virulence. |
| 资助项目 | 上海市自然科学基金青年项目[00000000] ; 中国科学院百人计划项目资助[00000000] |
| WOS研究方向 | Science & Technology - Other Topics (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:5012885 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269362]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Lan Lefu |
| 作者单位 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Chen Feifei,Di Hongxia,Lan Lefu. Small molecules targeting Staphylococcus aureus virulence[J]. Chinese Science Bulletin,2013,58(36):3743-3752. |
| APA | Chen Feifei,Di Hongxia,&Lan Lefu.(2013).Small molecules targeting Staphylococcus aureus virulence.Chinese Science Bulletin,58(36),3743-3752. |
| MLA | Chen Feifei,et al."Small molecules targeting Staphylococcus aureus virulence".Chinese Science Bulletin 58.36(2013):3743-3752. |
入库方式： OAI收割
来源：上海药物研究所
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