Cinnamomols A and B, Immunostimulative Diterpenoids with a New Carbon Skeleton from the Leaves of Cinnamomum cassia
文献类型：期刊论文
| 作者 | Zhou, Lei2; Tuo, Yali2; Hao, Yi3; Guo, Xiaoman3; Tang, Wei1 ; Xue, Yongbo2; Zeng, Junfen2; Zhou, Yu1; Xiang, Ming2; Zuo, Jianping1
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2017-06-02 |
| 卷号 | 19期号:11页码:3029-3032 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.7b01323 |
| 文献子类 | Article |
| 英文摘要 | Two diterpenoids with an unprecedented diterpene carbon skeleton, cinnamomols A (1) and B (2), were isolated from the leaves of Cinnamomum cassia. 1 and 2 feature a cage-like, rigid, 5/5/5/5/5/6-fused hexacyclic ring system. The structures of 1 and 2 were established by extensive spectroscopic techniques and single-crystal X-ray diffraction, and their plausible biosynthetic pathways were proposed. 1 and 2 exhibited significant in vitro immunostimulative activity, and the mode of action of 1 was investigated. |
| WOS关键词 | THYMOSIN ALPHA-1 |
| 资助项目 | National Natural Science Foundation of China[31370372] ; Foundation of the Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, CAS[2008DP173091-2016-01] ; Fundamental Research Funds for the Central Universities[HUST: 2016YXMS148] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000402850900064 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272622]  |
| 专题 | 药理学第一研究室 药物化学研究室 |
| 通讯作者 | Yao, Guangmin; Zhang, Yonghui |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Huazhong Univ Sci & Technol, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China; 3.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Basic Med, Wuhan 430030, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhou, Lei,Tuo, Yali,Hao, Yi,et al. Cinnamomols A and B, Immunostimulative Diterpenoids with a New Carbon Skeleton from the Leaves of Cinnamomum cassia[J]. ORGANIC LETTERS,2017,19(11):3029-3032. |
| APA | Zhou, Lei.,Tuo, Yali.,Hao, Yi.,Guo, Xiaoman.,Tang, Wei.,...&Zhang, Yonghui.(2017).Cinnamomols A and B, Immunostimulative Diterpenoids with a New Carbon Skeleton from the Leaves of Cinnamomum cassia.ORGANIC LETTERS,19(11),3029-3032. |
| MLA | Zhou, Lei,et al."Cinnamomols A and B, Immunostimulative Diterpenoids with a New Carbon Skeleton from the Leaves of Cinnamomum cassia".ORGANIC LETTERS 19.11(2017):3029-3032. |
入库方式： OAI收割
来源：上海药物研究所
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