中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Ruthenium-Catalyzed Direct Hydroxymethylation of Aryl C-H Bonds

文献类型:期刊论文

作者Wu, Yunxiang1,2; Zhou, Bing1,2
刊名ACS CATALYSIS
出版日期2017-03
卷号7期号:3页码:2213-2217
关键词C-H activation ruthenium hydroxymethylation hydroxymethylarene formaldehyde
ISSN号2155-5435
DOI10.1021/acscatal.7b00078
文献子类Article
英文摘要An ideal addition of "inert" aryl C-H bonds to formaldehyde has been achieved to synthesize a variety of hydroxymethylarenes via a Ru(II)-catalyzed C-H activation. Many different directing groups (not limited to strongly heterocyclic directing groups) can be used, and this challenging C-H hydroxymethylation proceeds in the presence of water and air, without stoichiometric undesirable byproducts, thus offering an environmentally benign method of hydroxymethylarene synthesis that can be readily scaled up.
WOS关键词OXIDATIVE ORTHO-ACYLATION ; O-METHYL OXIMES ; HETEROAROMATIC BASES ; CONVERGENT SYNTHESIS ; ORTHO-ALKENYLATION ; RHODIUM CATALYSIS ; CYCLATIVE CAPTURE ; ROOM-TEMPERATURE ; ACTIVATION ; ALDEHYDES
资助项目CAS Pioneer Hundred Talents Program[00000000] ; "Personalized Medicines-Molecular Signature-based Drug Discovery and Development", Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020333]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000395726500085
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/272764]  
专题药物化学研究室
通讯作者Zhou, Bing
作者单位1.Chinese Acad Sci, SIMM, Dept Med Chem, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Wu, Yunxiang,Zhou, Bing. Ruthenium-Catalyzed Direct Hydroxymethylation of Aryl C-H Bonds[J]. ACS CATALYSIS,2017,7(3):2213-2217.
APA Wu, Yunxiang,&Zhou, Bing.(2017).Ruthenium-Catalyzed Direct Hydroxymethylation of Aryl C-H Bonds.ACS CATALYSIS,7(3),2213-2217.
MLA Wu, Yunxiang,et al."Ruthenium-Catalyzed Direct Hydroxymethylation of Aryl C-H Bonds".ACS CATALYSIS 7.3(2017):2213-2217.

入库方式: OAI收割

来源:上海药物研究所

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