Total Synthesis of (+)-Rutamarin
文献类型：期刊论文
| 作者 | Zhang, Yi-Nan2; Zhang, Shi-Lei3; Ma, Lei3; Zhang, Yu2; Shen, Xu2 ; Wang, Wei1,3; Hu, Li-Hong2
|
| 刊名 | ADVANCED SYNTHESIS & CATALYSIS
 |
| 出版日期 | 2008-10 |
| 卷号 | 350期号:14-15页码:2373-2379 |
| 关键词 | asymmetric synthesis furanocoumarins rutamarin Sharpless asymmetric dihydroxylation |
| ISSN号 | 1615-4150 |
| DOI | 10.1002/adsc.200800396 |
| 文献子类 | Article |
| 英文摘要 | The first enantioselective total synthesis of (+)-rutamarin (1) is described. The synthetic route features the highly enantioselective construction of the stereogenic center via the Sharpless asymmetric dihydroxylation (99% ee), the facile assembly of quaternary carbon-centered 3-substituted side chain and high synthetic efficiency from readily available starting materials. Furthermore, the synthetic strategy could be readily adopted for the synthesis of (+)-rutamarin analogues. |
| WOS关键词 | RUTAMARIN ; 3-(1',1'-DIMETHYLALLYL)COUMARINS |
| 资助项目 | Chinese NSFC[90713046] ; Chinese National High-tech RD Program[2007AA02Z147] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000260760700031 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272787]  |
| 专题 | 药理学第三研究室 药物化学研究室 上海中药现代化研究中心 |
| 通讯作者 | Zhang, Yu |
| 作者单位 | 1.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 3.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhang, Yi-Nan,Zhang, Shi-Lei,Ma, Lei,et al. Total Synthesis of (+)-Rutamarin[J]. ADVANCED SYNTHESIS & CATALYSIS,2008,350(14-15):2373-2379. |
| APA | Zhang, Yi-Nan.,Zhang, Shi-Lei.,Ma, Lei.,Zhang, Yu.,Shen, Xu.,...&Hu, Li-Hong.(2008).Total Synthesis of (+)-Rutamarin.ADVANCED SYNTHESIS & CATALYSIS,350(14-15),2373-2379. |
| MLA | Zhang, Yi-Nan,et al."Total Synthesis of (+)-Rutamarin".ADVANCED SYNTHESIS & CATALYSIS 350.14-15(2008):2373-2379. |
入库方式： OAI收割
来源：上海药物研究所
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