Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma
文献类型：期刊论文
| 作者 | Dong, Qun; Yao, Han; Fang, Ji-nian; Ding, Kan
|
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 2007-07-23 |
| 卷号 | 342期号:10页码:1343-1349 |
| 关键词 | polysacchcaride alpha-D-glucan arabinogalactan rhamnogalacturonan 1 Cistanche deserticola immunological activity |
| ISSN号 | 0008-6215 |
| DOI | 10.1016/j.carres.2007.03.017 |
| 文献子类 | Article |
| 英文摘要 | Two major polysaccharide fractions, CDA-1A and CDA-3B, were isolated from the cold-water extract of Cistanche deserticola Y. C. Ma, a holoparasitic plant and a valuable traditional Chinese medicine, using anion-exchange chromatography on DEAE-cellulose and gel-permeation chromatography on Sephacryl S-300 and Sephadex G-150. Their major structural features were elucidated using component and linkage analyses, periodate oxidation, Smith degradation, partial acid hydrolysis, and NMR spectroscopy. The results indicated that CDA-1A is an alpha-(1 -> 4)-D-glucan with alpha-(1 -> 6)-linked branches attached to the O-6 of branch points and that CDA-3B is an RG-I polysaccharide containing a typical rhamnogalacturonan backbone and arabinogalactan or arabinan branches. Bioactivity tests showed that CDA-1A is inert for T-cell proliferation stimulation but active for B-cell proliferation, while CDA-3B is potent for the stimulation of both T- and B-cell proliferation. (c) 2007 Elsevier Ltd. All rights reserved. |
| WOS关键词 | PECTIC ARABINOGALACTAN ; PHENYLETHANOIDS ; PROLIFERATION ; FEATURES ; ROOTS ; ASSAY |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000247296500007 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273197]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Ding, Kan |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dong, Qun,Yao, Han,Fang, Ji-nian,et al. Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma[J]. CARBOHYDRATE RESEARCH,2007,342(10):1343-1349. |
| APA | Dong, Qun,Yao, Han,Fang, Ji-nian,&Ding, Kan.(2007).Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma.CARBOHYDRATE RESEARCH,342(10),1343-1349. |
| MLA | Dong, Qun,et al."Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma".CARBOHYDRATE RESEARCH 342.10(2007):1343-1349. |
入库方式： OAI收割
来源：上海药物研究所
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