A convergent and stereoselective synthesis of a seco-precursor of macrolactin A
文献类型：期刊论文
| 作者 | Li, SK; Xiao, XS; Yan, XB; Liu, XJ; Xu, R; Bai, DL
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2005-11-21 |
| 卷号 | 61期号:47页码:11291-11298 |
| 关键词 | Homer-Emmons reaction seco-precursor macrolactin A |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2005.07.106 |
| 文献子类 | Article |
| 英文摘要 | A seco-precursor of macrolactin A was synthesized by coupling two advanced segments. Wittig reaction and Horner-Emmons reaction were utilized to construct the three characteristic E,Z and E,E dienes. The C-1-C-10 segment was synthesized through Horner-Emmons reaction with phosphonate reagent. The a-alkylation of sulfone stabilized anion with allyl bromide followed by desulfonation gave the C-11-C-24 segment. (c) 2005 Elsevier Ltd. All rights reserved. |
| WOS关键词 | Z-UNSATURATED ESTERS ; ORGANOIRON METHODOLOGY ; ENANTIOSELECTIVE SYNTHESIS ; METHOXYBENZYL ETHER ; DEPROTECTION ; FRAGMENT ; (-)-MACROLACTIN-A ; ESTERIFICATION ; LACTONIZATION ; MACROLIDES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000233150900023 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273771]  |
| 专题 | 院士及顾问专家 药物化学研究室 |
| 通讯作者 | Bai, DL |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, SK,Xiao, XS,Yan, XB,et al. A convergent and stereoselective synthesis of a seco-precursor of macrolactin A[J]. TETRAHEDRON,2005,61(47):11291-11298. |
| APA | Li, SK,Xiao, XS,Yan, XB,Liu, XJ,Xu, R,&Bai, DL.(2005).A convergent and stereoselective synthesis of a seco-precursor of macrolactin A.TETRAHEDRON,61(47),11291-11298. |
| MLA | Li, SK,et al."A convergent and stereoselective synthesis of a seco-precursor of macrolactin A".TETRAHEDRON 61.47(2005):11291-11298. |
入库方式： OAI收割
来源：上海药物研究所
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