Novel bone-targeted agents for treatment of osteoporosis
文献类型：期刊论文
| 作者 | Wang, JB; Yang, CH ; Yan, XM; Wu, XH; Xie, YY
|
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2005-07 |
| 卷号 | 16期号:7页码:859-862 |
| 关键词 | osteoporosis bone-targeted raloxifene bisphosphonate |
| ISSN号 | 1001-8417 |
| 文献子类 | Article |
| 英文摘要 | The novel bone-targeted agents were designed and synthesized by the combination of raloxifene and bisphosphonates. The anti-osteoporosis effect was evaluated by bone mineral density (BMD) obtained from OVX mice in vivo. The results indicated that the compound 8, 9 not only prevented ovariectomy induced loss of bone but also enhanced BMD to 0.87% and 19.67% compared to Sham, respectively. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000231036400003 |
| 出版者 | CHINESE CHEMICAL SOCIETY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273842]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Yang, CH |
| 作者单位 | CAS, State Key Lab Drug Discovery, SIBS, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, JB,Yang, CH,Yan, XM,et al. Novel bone-targeted agents for treatment of osteoporosis[J]. CHINESE CHEMICAL LETTERS,2005,16(7):859-862. |
| APA | Wang, JB,Yang, CH,Yan, XM,Wu, XH,&Xie, YY.(2005).Novel bone-targeted agents for treatment of osteoporosis.CHINESE CHEMICAL LETTERS,16(7),859-862. |
| MLA | Wang, JB,et al."Novel bone-targeted agents for treatment of osteoporosis".CHINESE CHEMICAL LETTERS 16.7(2005):859-862. |
入库方式： OAI收割
来源：上海药物研究所
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