Immunological activities and structure of pectin from Centella asiatica
文献类型：期刊论文
| 作者 | Wang, XS; Liu, L; Fang, JN |
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2005-04-07 |
| 卷号 | 60期号:1页码:95-101 |
| 关键词 | Centella asiatica pectin immunological activity acetyl group carboxyl group |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2004.11.031 |
| 文献子类 | Article |
| 英文摘要 | Centella asiatica, is mainly found in the south of Asia and the southern hemisphere. The pectin was extracted from C. asiatica and isolated by anion-exchange and gel-filtration chromatography with TLC and GLC analyses. It contained arabinose, rhamnose, galactose, xylose and galacturonic acid. The structural features were elucidated by partial acid hydrolysis, enzymatic degradation, methylation, carboxyl-reduction, NMR spectroscopy and ESI-MS experiments. The backbone was presumed to contain 1, 4-linked alpha-D-GalA and 1, 2/1, 2, 4-linked alpha-L-Rha with RG-I and homogalacturonan (HG) types. The side chains were neutral chains including arabinosyl, arabinogalactosyl and xylosyl chains. Most of the side chains were attached to Rha, while partial residues were presumed to link to GalA. 14% GalA residues in backbone contained acetyl groups. With deacetylation and carboxyl-reduction, the pectin and its degraded product showed immuno-stimulating activity to different extent in vitro. These results indicated that the carboxyl and acetyl groups play important roles in the expression of immunological activity. (c) 2004 Elsevier Ltd. All rights reserved. |
| WOS关键词 | ATRACTYLODES-LANCEA ; FEATURES ; RHIZOMES ; SYSTEM ; OLIGOSACCHARIDES ; POLYSACCHARIDES ; MONOSACCHARIDES ; DEGRADATION ; ROOTS |
| WOS研究方向 | Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000228351700013 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273887]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Fang, JN |
| 作者单位 | Chinese Acad Sci, Dept Organ, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, XS,Liu, L,Fang, JN. Immunological activities and structure of pectin from Centella asiatica[J]. CARBOHYDRATE POLYMERS,2005,60(1):95-101. |
| APA | Wang, XS,Liu, L,&Fang, JN.(2005).Immunological activities and structure of pectin from Centella asiatica.CARBOHYDRATE POLYMERS,60(1),95-101. |
| MLA | Wang, XS,et al."Immunological activities and structure of pectin from Centella asiatica".CARBOHYDRATE POLYMERS 60.1(2005):95-101. |
入库方式： OAI收割
来源：上海药物研究所
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