Novel spironolactone-analogs as impurities in spironolactone
文献类型：期刊论文
| 作者 | Chen, H; Wang, XY; Yang, ZD; Li, YC |
| 刊名 | STEROIDS
 |
| 出版日期 | 2004-09 |
| 卷号 | 69期号:10页码:647-652 |
| 关键词 | spironolactone steroids structure elucidation spectroscopic methods x-ray organic polysulfide |
| ISSN号 | 0039-128X |
| DOI | 10.1016/j.steriods.2004.05.018 |
| 文献子类 | Article |
| 英文摘要 | Six novel spironolactone-analogs steroids (3-8) were isolated from spironolactone by using various chromatographic methods. Their structures were elucidated by spectrometric analysis. Two of the analogs (3 and 7) were confirmed by X-ray crystallography. The A-ring of compounds 3-7 is opened at C-2-C-3 bond, and compound 7 is an organic polysulfide, which has a rare, nine-membered ring with a five sulfur atom bridge. (C) 2004 Published by Elsevier Inc. |
| WOS关键词 | PLASMA-RENIN ACTIVITY ; HYPERTENSION |
| WOS研究方向 | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 语种 | 英语 |
| WOS记录号 | WOS:000224623300007 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274031]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Li, YC |
| 作者单位 | 1.Beijing Univ Technol, Coll Life Sci, Beijing 100022, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, H,Wang, XY,Yang, ZD,et al. Novel spironolactone-analogs as impurities in spironolactone[J]. STEROIDS,2004,69(10):647-652. |
| APA | Chen, H,Wang, XY,Yang, ZD,&Li, YC.(2004).Novel spironolactone-analogs as impurities in spironolactone.STEROIDS,69(10),647-652. |
| MLA | Chen, H,et al."Novel spironolactone-analogs as impurities in spironolactone".STEROIDS 69.10(2004):647-652. |
入库方式： OAI收割
来源：上海药物研究所
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