Structure and potential immunological activity of a pectin from Centella asiatica (L.) Urban
文献类型：期刊论文
| 作者 | Wang, XS; Dong, Q; Zuo, JP ; Fang, JN
|
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 2003-10-31 |
| 卷号 | 338期号:22页码:2393-2402 |
| 关键词 | Centella asiatica polysaccharide pectin immunological activity structure-activity relationships modification |
| ISSN号 | 0008-6215 |
| DOI | 10.1016/S0008-6215(03)0080-X |
| 文献子类 | Article |
| 英文摘要 | S3A was a RG-I pectin isolated from Centella asiatica that contained Rha, Ara, Gal, Glc and GalA in molar ratio of 1.0:0.6:1.5:0.2:1.1 and had been found to have a backbone composed mainly of the disaccharide repeat unit, --> 4)-alpha-D-Galp A-(1--> 2)-alpha-L-Rhap-(1 -->. Based on methylation analysis, NaIO(4) oxidation, partial acid hydrolysis and lithium-treatment, the structural features were elucidated. Side chains of S3A were predominantly linked to O-4 of 1,2,4-linked alpha-L-Rhap. The side chains are comprised of arabinosyl chains, galactosyl chains, arabinogalactosyl chains and short glucosyl chains. A total of 45% Rhap in the backbone was substituted by side chains. The arabinosyl residues were mostly distributed in the arabinosyl side chains. According to the immunological results of S3A and its degraded derivatives, S3A had no immunological activity, but its derivatives had immunostimulating activities to some extent. (C) 2003 Elsevier Ltd. All rights reserved. |
| WOS关键词 | ACIDIC POLYSACCHARIDE ; RHAMNOGALACTURONAN-I ; ATRACTYLODES-LANCEA ; FEATURES ; SYSTEM ; SUBSTANCES ; FRAGMENTS ; RHIZOMES ; LITHIUM ; ROOTS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000186359700013 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274163]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Fang, JN |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, XS,Dong, Q,Zuo, JP,et al. Structure and potential immunological activity of a pectin from Centella asiatica (L.) Urban[J]. CARBOHYDRATE RESEARCH,2003,338(22):2393-2402. |
| APA | Wang, XS,Dong, Q,Zuo, JP,&Fang, JN.(2003).Structure and potential immunological activity of a pectin from Centella asiatica (L.) Urban.CARBOHYDRATE RESEARCH,338(22),2393-2402. |
| MLA | Wang, XS,et al."Structure and potential immunological activity of a pectin from Centella asiatica (L.) Urban".CARBOHYDRATE RESEARCH 338.22(2003):2393-2402. |
入库方式： OAI收割
来源：上海药物研究所
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