Recent Advances in the Synthesis of Heterocycles via Gold-catalyzed Cascade Reactions: A Review
文献类型：期刊论文
| 作者 | Gao, Feng1,2; Zhou, Yu1,2 ; Liu, Hong1,2
|
| 刊名 | CURRENT ORGANIC CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 21期号:15页码:1530-1566 |
| 关键词 | Gold transition metals cascade reactions tandem reactions domino reactions heterocycles natural products |
| ISSN号 | 1385-2728 |
| DOI | 10.2174/1385272821666170102144500 |
| 文献子类 | Review |
| 英文摘要 | Background: Heterocyclic scaffolds widely occur in natural products and pharmaceutical molecules and because of their broad biological activities, the synthesis of such frameworks with diverse approaches is one of the most attractive fields in modern organic chemistry. Recently, cascade reactions catalyzed by transition metals made astounding advances in the synthesis of heterocyclic compounds for their step economy. Among them, gold-catalyzed cascade reactions emerged as important tools to construct complicated heterocyclic architecture from simple precursors in the past decade. Objective: This review presents an overview of recent advances in gold-catalyzed cascade reactions to generate diverse heterocyclic scaffolds and its applications in total synthesis of natural products. |
| WOS关键词 | OXIDATION/1,2-ALKYNYL MIGRATION/CYCLIZATION CASCADE ; NITRO-MANNICH/HYDROAMINATION CASCADE ; FORMAL 4+2 CYCLOADDITION ; DIELS-ALDER REACTION ; ONE-POT SYNTHESIS ; GOLD(I)-CATALYZED CASCADE ; CYCLIZATION CASCADE ; EFFICIENT SYNTHESIS ; ENANTIOSELECTIVE SYNTHESIS ; HIGHLY EFFICIENT |
| 资助项目 | National Natural Science Foundation of China[81620108027] ; National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[91229204] ; National Natural Science Foundation of China[81220108025] ; Major Project of Chinese National Programs for Fundamental Research and Development[2015CB910304] ; National S&T Major Projects[2014ZX09507002-001] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000406672500006 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275703]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Liu, Hong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, Sch Pharm, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Feng,Zhou, Yu,Liu, Hong. Recent Advances in the Synthesis of Heterocycles via Gold-catalyzed Cascade Reactions: A Review[J]. CURRENT ORGANIC CHEMISTRY,2017,21(15):1530-1566. |
| APA | Gao, Feng,Zhou, Yu,&Liu, Hong.(2017).Recent Advances in the Synthesis of Heterocycles via Gold-catalyzed Cascade Reactions: A Review.CURRENT ORGANIC CHEMISTRY,21(15),1530-1566. |
| MLA | Gao, Feng,et al."Recent Advances in the Synthesis of Heterocycles via Gold-catalyzed Cascade Reactions: A Review".CURRENT ORGANIC CHEMISTRY 21.15(2017):1530-1566. |
入库方式： OAI收割
来源：上海药物研究所
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