Penicillanthone and penicillidic acids A-C from the soil-derived fungus Penicillium aculeatum PSU-RSPG105
文献类型：期刊论文
| 作者 | Daengrot, Charuwan1,6; Rukachaisirikul, Vatcharin1,6; Tadpetch, Kwanruthai1,6; Phongpaichit, Souwalak4,5; Bowornwiriyapan, Kawitsara4,5; Sakayaroj, Jariya3; Shen, Xu2
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:46页码:39700-39709 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c6ra04401h |
| 文献子类 | Article |
| 英文摘要 | A new xanthone (penicillanthone, 1) and three new diphenyl ether derivatives (penicillidic acids A-C, 2-4) together with 14 known compounds (5-18) were isolated from the soil-derived fungus Penicillium aculeatum PSU-RSPG105. The structures were elucidated by spectroscopic analyses. The absolute configuration of compound 1 was determined using the Snatzke's method whereas those of compounds 2-4 was established by comparison of their optical rotations with those of structurally related compounds. Compound 5 exhibited mild antimycobacterial activity against Mycobacterium tuberculosis with an MIC value of 25 mu g mL (1) and was noncytotoxic to noncancerous Vero cells. In addition, altenusin (12) displayed moderate antibacterial activity against methicillin-resistant Staphylococcus aureus with an MIC value of 32 mu g mL(-1) and mild activity towards Vero cells with an IC50 value of 19.46 mu M. |
| WOS关键词 | DIPHENYL ETHER DERIVATIVES ; TALAROMYCES SP ; XANTHONE DERIVATIVES ; PURPACTIN-A ; SP MA-37 ; METABOLITES ; BIOSYNTHESIS ; BENZOPHENONE ; PURPUROGENUM ; PINOPHILUM |
| 资助项目 | Office of the Higher Education Commission, Thailand[00000000] ; Princess of Naradhiwas University[00000000] ; Thailand Research Fund (TRF)[DBG5680001] ; Center of Excellence for Innovation in Chemistry (PERCH-CIC)[00000000] ; Prince of Songkla University[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000374974300023 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276235]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Rukachaisirikul, Vatcharin |
| 作者单位 | 1.Prince Songkla Univ, Dept Chem, Hat Yai 90112, Thailand; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 3.Natl Ctr Genet Engn & Biotechnol BIOTEC, Thailand Sci Pk, Khlong Luang 12120, Pathum Thani, Thailand; 4.Prince Songkla Univ, Dept Microbiol, Fac Sci, Hat Yai 90112, Thailand; 5.Prince Songkla Univ, Nat Prod Res Ctr Excellence, Hat Yai 90112, Thailand; 6.Prince Songkla Univ, Fac Sci, Ctr Excellence Innovat Chem, Hat Yai 90112, Thailand; |
| 推荐引用方式 GB/T 7714 | Daengrot, Charuwan,Rukachaisirikul, Vatcharin,Tadpetch, Kwanruthai,et al. Penicillanthone and penicillidic acids A-C from the soil-derived fungus Penicillium aculeatum PSU-RSPG105[J]. RSC ADVANCES,2016,6(46):39700-39709. |
| APA | Daengrot, Charuwan.,Rukachaisirikul, Vatcharin.,Tadpetch, Kwanruthai.,Phongpaichit, Souwalak.,Bowornwiriyapan, Kawitsara.,...&Shen, Xu.(2016).Penicillanthone and penicillidic acids A-C from the soil-derived fungus Penicillium aculeatum PSU-RSPG105.RSC ADVANCES,6(46),39700-39709. |
| MLA | Daengrot, Charuwan,et al."Penicillanthone and penicillidic acids A-C from the soil-derived fungus Penicillium aculeatum PSU-RSPG105".RSC ADVANCES 6.46(2016):39700-39709. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。