Metal-mediate reactions based formal synthesis of triptonide and triptolide
文献类型：期刊论文
| 作者 | Xu, Hongtao; Tang, Huanyu; Feng, Huijin ; Li, Yuanchao
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2014-12-17 |
| 卷号 | 55期号:51页码:7118-7120 |
| 关键词 | Diterpenoid Triptolide Triptonide Metal Synthesis |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2014.11.010 |
| 文献子类 | Article |
| 英文摘要 | A formal synthesis of triptolide and triptonide has been achieved based on metal-mediate reactions. Specially, Noyori's ruthenium catalyzed enantioselective transfer hydrogenation, indium(III) catalyzed cationic polyene cyclization, palladium catalyzed carbonylation, rhodium catalyzed double bond migration, and palladium catalyzed ortho sp(2) C-H bond oxygenation reactions served as convenient entry points for the preparation of the tetracyclic building blocks and the C14 hydroxyl group. (C) 2014 Elsevier Ltd. All rights reserved. |
| WOS关键词 | PALLADIUM-CATALYZED CARBONYLATION ; ASYMMETRIC TRANSFER HYDROGENATION ; TRIPTERYGIUM-WILFORDII ; KETONES ; (-)-TRIPTOLIDE ; ACID ; OXYGENATION ; LACTONES ; DESIGN ; ACCESS |
| 资助项目 | Shanghai Science and Technology Commission 'biomedicine technology support project', China[13431900403] ; National Natural Science Foundation of NFSC, China[81373479] ; Specific Research Construction Project of National Clinical Research Base of TCM, China[JDZX2012010] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000347020100038 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276798]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Li, Yuanchao |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Hongtao,Tang, Huanyu,Feng, Huijin,et al. Metal-mediate reactions based formal synthesis of triptonide and triptolide[J]. TETRAHEDRON LETTERS,2014,55(51):7118-7120. |
| APA | Xu, Hongtao,Tang, Huanyu,Feng, Huijin,&Li, Yuanchao.(2014).Metal-mediate reactions based formal synthesis of triptonide and triptolide.TETRAHEDRON LETTERS,55(51),7118-7120. |
| MLA | Xu, Hongtao,et al."Metal-mediate reactions based formal synthesis of triptonide and triptolide".TETRAHEDRON LETTERS 55.51(2014):7118-7120. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。