Rhodium(III)-Catalyzed Intramolecular Redox-Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (+/-)-Goniomitine
文献类型：期刊论文
| 作者 | Zhou, Bing ; Du, Juanjuan; Yang, Yaxi; Li, Yuanchao
|
| 刊名 | CHEMISTRY-A EUROPEAN JOURNAL
 |
| 出版日期 | 2014-09-26 |
| 卷号 | 20期号:40页码:12768-12772 |
| 关键词 | C-H activation goniomitine indoles redox-neutral total synthesis |
| ISSN号 | 0947-6539 |
| DOI | 10.1002/chem.201403973 |
| 文献子类 | Article |
| 英文摘要 | A Rh-III-catalyzed intramolecular redox-neutral atom-economic annulation of a tethered alkyne has been developed to efficiently construct 2-amidealkyl indoles with completely reversed regioselectivity by a C-H activation pathway. Furthermore, using the Rh-III-catalyzed C-H activation/annulation as a key step, a one-pot synthesis of pyrido[1,2-a] indoles has also been developed and applied to a highly efficient formal total synthesis of (+/-)-goniomitine. |
| WOS关键词 | C-H ACTIVATION ; NONREARRANGED MONOTERPENOID UNIT ; SIMPLE INDOLE ALKALOIDS ; N BOND FORMATION ; O-METHYL OXIMES ; INTERNAL ALKYNES ; REGIOSELECTIVE SYNTHESIS ; EFFICIENT SYNTHESIS ; ROOM-TEMPERATURE ; DIRECTING GROUP |
| 资助项目 | National Natural Science Foundation of China[21302200] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000342627300012 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276894]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Zhou, Bing |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Bing,Du, Juanjuan,Yang, Yaxi,et al. Rhodium(III)-Catalyzed Intramolecular Redox-Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (+/-)-Goniomitine[J]. CHEMISTRY-A EUROPEAN JOURNAL,2014,20(40):12768-12772. |
| APA | Zhou, Bing,Du, Juanjuan,Yang, Yaxi,&Li, Yuanchao.(2014).Rhodium(III)-Catalyzed Intramolecular Redox-Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (+/-)-Goniomitine.CHEMISTRY-A EUROPEAN JOURNAL,20(40),12768-12772. |
| MLA | Zhou, Bing,et al."Rhodium(III)-Catalyzed Intramolecular Redox-Neutral Annulation of Tethered Alkynes: Formal Total Synthesis of (+/-)-Goniomitine".CHEMISTRY-A EUROPEAN JOURNAL 20.40(2014):12768-12772. |
入库方式： OAI收割
来源：上海药物研究所
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