Rh(III)-Catalyzed Intramolecular Redox-Neutral or Oxidative Cyclization of Alkynes: Short, Efficient Synthesis of 3,4-Fused Indole Skeletons
文献类型：期刊论文
| 作者 | Zhou, Bing ; Yang, Yaxi; Tang, Huanyu; Du, Juanjuan; Feng, Huijin; Li, Yuanchao
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2014-08-01 |
| 卷号 | 16期号:15页码:3900-3903 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol501599j |
| 文献子类 | Article |
| 英文摘要 | A Rh(III)-catalyzed intramolecular redox-neutral or oxidative annulation of a tethered alkyne has been developed to efficiently construct 3,4-fused indoles via a C-H activation pathway. The advantages of this process are (1) ready availability of annulation precursors; (2) broad substrate scope; (3) complete regioselectivity; (4) simple and mild reaction conditions; and (5) no need for an external oxidant or to employ molecular oxygen as the stoichiometric terminal oxidant. |
| WOS关键词 | C-H ACTIVATION ; PALLADIUM-CATALYZED REACTIONS ; N BOND FORMATION ; O-METHYL OXIMES ; INTERNAL ALKYNES ; ROOM-TEMPERATURE ; RHODIUM(III)-CATALYZED SYNTHESIS ; (+/-)-COMMUNESIN F ; (+)-LYSERGIC ACID ; TRICYCLIC INDOLES |
| 资助项目 | National Natural Science Foundation of China[21302200] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000339982300013 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276969]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Zhou, Bing |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Bing,Yang, Yaxi,Tang, Huanyu,et al. Rh(III)-Catalyzed Intramolecular Redox-Neutral or Oxidative Cyclization of Alkynes: Short, Efficient Synthesis of 3,4-Fused Indole Skeletons[J]. ORGANIC LETTERS,2014,16(15):3900-3903. |
| APA | Zhou, Bing,Yang, Yaxi,Tang, Huanyu,Du, Juanjuan,Feng, Huijin,&Li, Yuanchao.(2014).Rh(III)-Catalyzed Intramolecular Redox-Neutral or Oxidative Cyclization of Alkynes: Short, Efficient Synthesis of 3,4-Fused Indole Skeletons.ORGANIC LETTERS,16(15),3900-3903. |
| MLA | Zhou, Bing,et al."Rh(III)-Catalyzed Intramolecular Redox-Neutral or Oxidative Cyclization of Alkynes: Short, Efficient Synthesis of 3,4-Fused Indole Skeletons".ORGANIC LETTERS 16.15(2014):3900-3903. |
入库方式： OAI收割
来源：上海药物研究所
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