中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata

文献类型:期刊论文

作者Shi, Lei1,2,3; Dong, Qun2; Ding, Kan2
刊名FOOD CHEMISTRY
出版日期2014-06-01
卷号152页码:291-296
关键词Cudrania tricuspidata Xylan Structure Immunomodulatory activity Purification
ISSN号0308-8146
DOI10.1016/j.foodchem.2013.11.091
文献子类Article
英文摘要To discover new immunomodulator in the food industry, a water-soluble polysaccharide, CTPB1 was obtained from roots of Cudrania tricuspidata (Carr.) Bur. The average molecular weight of this polysaccharide was estimated to be 4.0 x 10(4) Da. Monosaccharide composition analysis indicated that the only neutral sugar present in this polysaccharide was xylose. From methylation analysis and H-1 and C-13 NMR spectroscopy, the structure of CTPB1 was deduced to be (4-O-methyl-n-glucurono)-D-xylan, with the 4-O-methyl-D-glucopyranosyluronic acid group linked to O-2 of a (1 -> 4)-beta-D-xylan. The repeating unit of CTPB1 is composed of one non-reducing terminal residue of 4-O-methyl-D-glucuronic acid on every four xylose residues. Immunomodulatory activity assays in vitro showed that CTPB1 may induce the proliferation of mouse splenocytes. It was suggested that CTPB1 could be a potential immunostimulant used in the food industry. (C) 2013 Elsevier Ltd. All rights reserved.
WOS关键词PRICKLY PEAR FRUITS ; XANTHONES ; (4-O-METHYL-D-GLUCURONO)-D-XYLAN ; MONOSACCHARIDES ; PERICARP ; SEEDS
资助项目National Natural Science Foundation of China (NSFC)[30970640] ; National Science Fund for Distinguished Young Scholars[81125025] ; Knowledge Innovation Program of the Chinese Academy of Sciences[SIMM0912QN-10]
WOS研究方向Chemistry ; Food Science & Technology ; Nutrition & Dietetics
语种英语
WOS记录号WOS:000332132300041
出版者ELSEVIER SCI LTD
源URL[http://119.78.100.183/handle/2S10ELR8/277064]  
专题药理学第三研究室
国家新药筛选中心
通讯作者Shi, Lei
作者单位1.Qufu Normal Univ, Coll Life Sci, Qufu 273165, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
3.Temasek Polytech, Temasek Appl Sci Sch, Singapore 529757, Singapore
推荐引用方式
GB/T 7714
Shi, Lei,Dong, Qun,Ding, Kan. Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata[J]. FOOD CHEMISTRY,2014,152:291-296.
APA Shi, Lei,Dong, Qun,&Ding, Kan.(2014).Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata.FOOD CHEMISTRY,152,291-296.
MLA Shi, Lei,et al."Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata".FOOD CHEMISTRY 152(2014):291-296.

入库方式: OAI收割

来源:上海药物研究所

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