Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata
文献类型:期刊论文
作者 | Shi, Lei1,2,3; Dong, Qun2; Ding, Kan2![]() |
刊名 | FOOD CHEMISTRY
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出版日期 | 2014-06-01 |
卷号 | 152页码:291-296 |
关键词 | Cudrania tricuspidata Xylan Structure Immunomodulatory activity Purification |
ISSN号 | 0308-8146 |
DOI | 10.1016/j.foodchem.2013.11.091 |
文献子类 | Article |
英文摘要 | To discover new immunomodulator in the food industry, a water-soluble polysaccharide, CTPB1 was obtained from roots of Cudrania tricuspidata (Carr.) Bur. The average molecular weight of this polysaccharide was estimated to be 4.0 x 10(4) Da. Monosaccharide composition analysis indicated that the only neutral sugar present in this polysaccharide was xylose. From methylation analysis and H-1 and C-13 NMR spectroscopy, the structure of CTPB1 was deduced to be (4-O-methyl-n-glucurono)-D-xylan, with the 4-O-methyl-D-glucopyranosyluronic acid group linked to O-2 of a (1 -> 4)-beta-D-xylan. The repeating unit of CTPB1 is composed of one non-reducing terminal residue of 4-O-methyl-D-glucuronic acid on every four xylose residues. Immunomodulatory activity assays in vitro showed that CTPB1 may induce the proliferation of mouse splenocytes. It was suggested that CTPB1 could be a potential immunostimulant used in the food industry. (C) 2013 Elsevier Ltd. All rights reserved. |
WOS关键词 | PRICKLY PEAR FRUITS ; XANTHONES ; (4-O-METHYL-D-GLUCURONO)-D-XYLAN ; MONOSACCHARIDES ; PERICARP ; SEEDS |
资助项目 | National Natural Science Foundation of China (NSFC)[30970640] ; National Science Fund for Distinguished Young Scholars[81125025] ; Knowledge Innovation Program of the Chinese Academy of Sciences[SIMM0912QN-10] |
WOS研究方向 | Chemistry ; Food Science & Technology ; Nutrition & Dietetics |
语种 | 英语 |
WOS记录号 | WOS:000332132300041 |
出版者 | ELSEVIER SCI LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/277064] ![]() |
专题 | 药理学第三研究室 国家新药筛选中心 |
通讯作者 | Shi, Lei |
作者单位 | 1.Qufu Normal Univ, Coll Life Sci, Qufu 273165, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 3.Temasek Polytech, Temasek Appl Sci Sch, Singapore 529757, Singapore |
推荐引用方式 GB/T 7714 | Shi, Lei,Dong, Qun,Ding, Kan. Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata[J]. FOOD CHEMISTRY,2014,152:291-296. |
APA | Shi, Lei,Dong, Qun,&Ding, Kan.(2014).Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata.FOOD CHEMISTRY,152,291-296. |
MLA | Shi, Lei,et al."Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata".FOOD CHEMISTRY 152(2014):291-296. |
入库方式: OAI收割
来源:上海药物研究所
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