Neoglycopeptide Synthesis by Suzuki-Miyaura Couplings between Glycosyl Aryl Boronic Acids and Iodopeptides
文献类型:期刊论文
作者 | Chen, Guohua1; Gu, Xiangying1,3; Chen, Lin3; Wang, Xin3![]() ![]() |
刊名 | PROTEIN AND PEPTIDE LETTERS
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出版日期 | 2014 |
卷号 | 21期号:10页码:1004-1010 |
关键词 | Glycosyl aryl boronic acids glycopeptides iodo peptides neoglycopeptides Suzuki-Miyaura coupling |
ISSN号 | 0929-8665 |
DOI | 10.2174/0929866521666140626103204 |
文献子类 | Article |
英文摘要 | Suzuki-Miyaura coupling reaction was applied in the syntheses of neoglycopeptides. This work utilizes new type of glycosyl aryl boronic acid and readily accessible iodo amino acids/iodopeptides. Both carbohydrate and peptide moieties are unprotected and the final product could be isolated directly. The neoglyco amino acid and neoglycopeptide products feature an O-glycosyl biaryl linker between the carbohydrate and peptide moieties. |
WOS关键词 | PHASE PEPTIDE-SYNTHESIS ; SOLID-PHASE ; AMINO-ACIDS ; GLYCOPEPTIDE ; MIMETICS ; 3'-IODO-L-TYROSINE ; GLYCOPROTEIN ; DERIVATIVES ; LIGATION ; PROTEINS |
资助项目 | National Natural Science Foundation of China[81102306] ; National Natural Science Foundation of China[81271634] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program" in China[2012ZX09301001] ; Hunan Provincial Natural Science Foundation of China[12JJ1012] |
WOS研究方向 | Biochemistry & Molecular Biology |
语种 | 英语 |
WOS记录号 | WOS:000341871000006 |
出版者 | BENTHAM SCIENCE PUBL LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/277266] ![]() |
专题 | 药物化学研究室 |
通讯作者 | Chen, Guohua |
作者单位 | 1.China Pharmaceut Univ, Sch Pharm, Nanjing 210009, Jiangsu, Peoples R China; 2.Cent S Univ, Sch Pharmaceut Sci, Changsha 410013, Hunan, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
推荐引用方式 GB/T 7714 | Chen, Guohua,Gu, Xiangying,Chen, Lin,et al. Neoglycopeptide Synthesis by Suzuki-Miyaura Couplings between Glycosyl Aryl Boronic Acids and Iodopeptides[J]. PROTEIN AND PEPTIDE LETTERS,2014,21(10):1004-1010. |
APA | Chen, Guohua.,Gu, Xiangying.,Chen, Lin.,Wang, Xin.,Chen, Yue-Lei.,...&Zeng, Wenbin.(2014).Neoglycopeptide Synthesis by Suzuki-Miyaura Couplings between Glycosyl Aryl Boronic Acids and Iodopeptides.PROTEIN AND PEPTIDE LETTERS,21(10),1004-1010. |
MLA | Chen, Guohua,et al."Neoglycopeptide Synthesis by Suzuki-Miyaura Couplings between Glycosyl Aryl Boronic Acids and Iodopeptides".PROTEIN AND PEPTIDE LETTERS 21.10(2014):1004-1010. |
入库方式: OAI收割
来源:上海药物研究所
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