Copper-mediated C-H(sp(2))/C-H(sp(3)) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold
文献类型：期刊论文
| 作者 | Zhu, Wei; Zhang, Dengyou; Yang, Nan ; Liu, Hong
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2014 |
| 卷号 | 50期号:73页码:10634-10636 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c4cc03837a |
| 文献子类 | Article |
| 英文摘要 | A facile, copper-mediated, direct C-H(sp(2))/C-H(sp(3)) bond coupling of benzoic acid derivatives with ethyl cyanoacetate by the deployment of an 8-aminoquinoline moiety as a bidentate directing group is disclosed. Such a unique transformation provides a new strategy for the construction of an isoquinolinone scaffold as one of the privileged cores. |
| WOS关键词 | C-H BONDS ; DIRECT FUNCTIONALIZATION ; DIRECTING GROUP ; ACTIVATION ; ARYL ; ARYLATION ; ARENE ; ALKALOIDS ; HALIDES |
| 资助项目 | National Natural Science Foundation of China[21021063] ; National Natural Science Foundation of China[91229204] ; National Natural Science Foundation of China[81025017] ; National S&T Major Projects - Program of Shanghai Subject Chief Scientist[2012ZX09103101-072] ; National S&T Major Projects - Program of Shanghai Subject Chief Scientist[2013ZX09507-001] ; National S&T Major Projects - Program of Shanghai Subject Chief Scientist[2014ZX0950 7002-001] ; National S&T Major Projects - Program of Shanghai Subject Chief Scientist[12XD1407100] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000340899500019 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277270]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Liu, Hong |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Wei,Zhang, Dengyou,Yang, Nan,et al. Copper-mediated C-H(sp(2))/C-H(sp(3)) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold[J]. CHEMICAL COMMUNICATIONS,2014,50(73):10634-10636. |
| APA | Zhu, Wei,Zhang, Dengyou,Yang, Nan,&Liu, Hong.(2014).Copper-mediated C-H(sp(2))/C-H(sp(3)) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold.CHEMICAL COMMUNICATIONS,50(73),10634-10636. |
| MLA | Zhu, Wei,et al."Copper-mediated C-H(sp(2))/C-H(sp(3)) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold".CHEMICAL COMMUNICATIONS 50.73(2014):10634-10636. |
入库方式： OAI收割
来源：上海药物研究所
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