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Stereospecific Synthesis of Drospirenone

文献类型：期刊论文

作者Deng, Gang2; Huang, Zuogang1; Zhao, Xiaolong2; Li, Zheng3; Li, Yuanchao3; Jiang, Biao1,2
刊名CHINESE JOURNAL OF CHEMISTRY
出版日期2013-01
卷号31期号:1页码:15-17
关键词drospirenone stereospecific synthesis ionic hydrogenation Oppenauer oxidation cyclopropanation
ISSN号1001-604X
DOI10.1002/cjoc.201201147
文献子类Article
英文摘要A procedure for the stereospecific synthesis of drospirenone has been developed. The key steps included the stereospecific reduction of the C7-tertiary alcohol with ZnI2/Et3SiH, a novel mild and stereospecific tertiary alcohol reduction system, and the tandem oxidation/cyclopropanation reactions.
WOS关键词ALDOSTERONE-ANTAGONIST ; SPIRORENONE ; ROUTE
资助项目China Postdoctoral Science Foundation[00000000] ; National Basic Research Program of China[2010CB833200] ; National Basic Research Program of China[2010CB833300] ; National Natural Science Foundation of China[20832007] ; National Natural Science Foundation of China[21102167] ; Science and Technology Commission of Shanghai Municipality[12DZ1930902] ; Chinese Academy of Sciences[00000000]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000313811800005
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/277811]  
专题药物化学研究室
通讯作者Li, Yuanchao
作者单位1.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai 201210, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Deng, Gang,Huang, Zuogang,Zhao, Xiaolong,et al. Stereospecific Synthesis of Drospirenone[J]. CHINESE JOURNAL OF CHEMISTRY,2013,31(1):15-17.
APA Deng, Gang,Huang, Zuogang,Zhao, Xiaolong,Li, Zheng,Li, Yuanchao,&Jiang, Biao.(2013).Stereospecific Synthesis of Drospirenone.CHINESE JOURNAL OF CHEMISTRY,31(1),15-17.
MLA Deng, Gang,et al."Stereospecific Synthesis of Drospirenone".CHINESE JOURNAL OF CHEMISTRY 31.1(2013):15-17.

入库方式： OAI收割

来源：上海药物研究所

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