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FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization

文献类型：期刊论文

作者Zhang, Jing1; Wu, Kui2; Wang, Meining1; Jiang, Jianqin2; Zhang, Ao1
刊名TETRAHEDRON
出版日期2011-02-04
卷号67期号:5页码:842-848
关键词1-Substituted benzazepine Tetrahydroisoquinoline Ring arrangement Iron (III) chloride Tetrahydropyrimidin-4(1H)-one
ISSN号0040-4020
DOI10.1016/j.tet.2010.12.038
文献子类Article
英文摘要FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines was further exploited. Both 1-aryl- and 1-alkyl- or 1-alkenyl-benzazepines underwent this reaction smoothly. The rearrangement products were used to prepare a series of novel derivatives containing both tetrahydroisoquinoline (THIQ) and tetrahydropyrimidin-4(1H)-one scaffolds through a Mannich-type process. (C) 2010 Elsevier Ltd. All rights reserved.
WOS关键词DERIVATIVES
资助项目Chinese National Science Foundation[30772625] ; Chinese National Science Foundation[81072528] ; Shanghai Commission of Science and Technology[10410702600] ; Shanghai Commission of Science and Technology[10JC1417100] ; Shanghai Commission of Science and Technology[10dz1910104] ; National Science & Technology Major Project on 'Key New Drug Creation and Manufacturing Program'[2009ZX09301-001] ; National Science & Technology Major Project on 'Key New Drug Creation and Manufacturing Program'[2009ZX09103-062]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000286995800005
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/278606]  
专题药物化学研究室
通讯作者Jiang, Jianqin
作者单位1.China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Peoples R China;
2.Chinese Acad Sci, SOMCL, SIMM, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Jing,Wu, Kui,Wang, Meining,et al. FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization[J]. TETRAHEDRON,2011,67(5):842-848.
APA Zhang, Jing,Wu, Kui,Wang, Meining,Jiang, Jianqin,&Zhang, Ao.(2011).FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization.TETRAHEDRON,67(5),842-848.
MLA Zhang, Jing,et al."FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization".TETRAHEDRON 67.5(2011):842-848.

入库方式： OAI收割

来源：上海药物研究所

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