First total synthesis of tripdiolide
文献类型:期刊论文
| 作者 | Zhou, Bing ; Tang, Huanyu; Feng, Huijin ; Li, Yuanchao
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| 刊名 | TETRAHEDRON
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| 出版日期 | 2011-02-04 |
| 卷号 | 67期号:5页码:904-909 |
| 关键词 | Tripdiolide Total synthesis Abietic acid Tripterygium wilfordii Hook. f. alpha,beta-Unsaturated lactone ring |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2010.12.014 |
| 文献子类 | Article |
| 英文摘要 | The first total synthesis of tripdiolide 1 from the readily available abietic acid 3 in 22 steps is described and this synthesis furnishes a 5.8% overall yield of 1 with an average yield of 87%. (C) 2010 Elsevier Ltd. All rights reserved. |
| WOS关键词 | WILFORDII HOOK-F ; TRIPTERYGIUM-WILFORDII ; RING-SYSTEM ; TRIPTOLIDE ; TRIPTONIDE ; COMPONENTS ; APOPTOSIS ; OXIDATION ; ALDEHYDES |
| 资助项目 | National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program', China[2009ZX09102-026] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000286995800015 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278607] ![]() |
| 专题 | 药物化学研究室 |
| 通讯作者 | Li, Yuanchao |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Bing,Tang, Huanyu,Feng, Huijin,et al. First total synthesis of tripdiolide[J]. TETRAHEDRON,2011,67(5):904-909. |
| APA | Zhou, Bing,Tang, Huanyu,Feng, Huijin,&Li, Yuanchao.(2011).First total synthesis of tripdiolide.TETRAHEDRON,67(5),904-909. |
| MLA | Zhou, Bing,et al."First total synthesis of tripdiolide".TETRAHEDRON 67.5(2011):904-909. |
入库方式: OAI收割
来源:上海药物研究所
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