First total synthesis of tripdiolide
文献类型:期刊论文
作者 | Zhou, Bing![]() ![]() |
刊名 | TETRAHEDRON
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出版日期 | 2011-02-04 |
卷号 | 67期号:5页码:904-909 |
关键词 | Tripdiolide Total synthesis Abietic acid Tripterygium wilfordii Hook. f. alpha,beta-Unsaturated lactone ring |
ISSN号 | 0040-4020 |
DOI | 10.1016/j.tet.2010.12.014 |
文献子类 | Article |
英文摘要 | The first total synthesis of tripdiolide 1 from the readily available abietic acid 3 in 22 steps is described and this synthesis furnishes a 5.8% overall yield of 1 with an average yield of 87%. (C) 2010 Elsevier Ltd. All rights reserved. |
WOS关键词 | WILFORDII HOOK-F ; TRIPTERYGIUM-WILFORDII ; RING-SYSTEM ; TRIPTOLIDE ; TRIPTONIDE ; COMPONENTS ; APOPTOSIS ; OXIDATION ; ALDEHYDES |
资助项目 | National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program', China[2009ZX09102-026] |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000286995800015 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/278607] ![]() |
专题 | 药物化学研究室 |
通讯作者 | Li, Yuanchao |
作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Zhou, Bing,Tang, Huanyu,Feng, Huijin,et al. First total synthesis of tripdiolide[J]. TETRAHEDRON,2011,67(5):904-909. |
APA | Zhou, Bing,Tang, Huanyu,Feng, Huijin,&Li, Yuanchao.(2011).First total synthesis of tripdiolide.TETRAHEDRON,67(5),904-909. |
MLA | Zhou, Bing,et al."First total synthesis of tripdiolide".TETRAHEDRON 67.5(2011):904-909. |
入库方式: OAI收割
来源:上海药物研究所
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