Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active alpha-Allenylglycines
文献类型：期刊论文
| 作者 | Jin, Shen-Shuang; Xu, Ming-Hua
|
| 刊名 | ADVANCED SYNTHESIS & CATALYSIS
 |
| 出版日期 | 2010-12-17 |
| 卷号 | 352期号:18页码:3136-3140 |
| 关键词 | allenylation alpha-allenylglycine N-tert-butanesulfinyl imino ester indium cis-substituted proline |
| ISSN号 | 1615-4150 |
| DOI | 10.1002/adsc.201000688 |
| 文献子类 | Article |
| 英文摘要 | An efficient and practical asymmetric synthesis of highly enantiomerically enriched alpha-allenylglycines by room temperature indium-mediated allenylation of chiral N-tert-butanesulfinyl imino esters with propargylic halides is described. The synthetic utilities of the approach were demonstrated by the rapid and convenient preparation of challenging cis-substituted proline derivatives. |
| WOS关键词 | ENOLATE CLAISEN REARRANGEMENT ; CONCISE ASYMMETRIC-SYNTHESIS ; AMINO-ACIDS ; BIS(SULFINYL)IMIDOAMIDINE LIGANDS ; STEREOSELECTIVE-SYNTHESIS ; CATALYZED-REACTIONS ; VICINAL DIAMINES ; ALLENES ; ALCOHOLS ; ALDEHYDES |
| 资助项目 | National Natural Science Foundation of China[20721003] ; Chinese Academy of Sciences[00000000] ; State key Laboratory of Drug Research, SIMM[00000000] ; National Science & Technology Major Project[2009ZX09301-001] ; National Science & Technology Major Project[2008ZX09401-004] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000285397800007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278687]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Xu, Ming-Hua |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Shen-Shuang,Xu, Ming-Hua. Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active alpha-Allenylglycines[J]. ADVANCED SYNTHESIS & CATALYSIS,2010,352(18):3136-3140. |
| APA | Jin, Shen-Shuang,&Xu, Ming-Hua.(2010).Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active alpha-Allenylglycines.ADVANCED SYNTHESIS & CATALYSIS,352(18),3136-3140. |
| MLA | Jin, Shen-Shuang,et al."Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active alpha-Allenylglycines".ADVANCED SYNTHESIS & CATALYSIS 352.18(2010):3136-3140. |
入库方式： OAI收割
来源：上海药物研究所
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