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Synthesis of novel analogues of zanamivir as neuraminidase inhibitors

文献类型：期刊论文

作者Xiong, Rui Sheng1; Zhao, Qing Jie1; Zhu, Hang Hang2; Liu, Zheng3; Wei, Ya Bing2; Shen, Jing Shan1,3
刊名CHINESE CHEMICAL LETTERS
出版日期2010-11
卷号21期号:11页码:1338-1341
关键词Zanamivir Triazole Click chemistry
ISSN号1001-8417
DOI10.1016/j.cclet.2010.06.021
文献子类Article
英文摘要A versatile synthesis of novel zanamivir analogues modified at C-4 and C-8 positions was described. The formation of amides from the acid with corresponding amines, followed by click chemistry generated the triazole substituted compounds as novel analogues of neuraminidase inhibitors in good yields. (C) 2010 Jing Shan Shen. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
WOS关键词INFLUENZA-VIRUS NEURAMINIDASE ; STRUCTURAL-ANALYSIS ; CLICK CHEMISTRY ; DESIGN ; ACID ; DISCOVERY ; POTENT ; DERIVATIVES ; SIALIDASES ; SERIES
资助项目Ministry of Science & Technology of China[2006BAI01B02]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000283899700020
出版者ELSEVIER SCIENCE INC
源URL[http://119.78.100.183/handle/2S10ELR8/278735]  
专题药物化学研究室
通讯作者Shen, Jing Shan
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
2.Nanjing Univ Technol, Coll Mat Sci & Engn, Nanjing 210009, Peoples R China;
3.Topharman Shanghai Co Ltd, Shanghai 201209, Peoples R China
推荐引用方式
GB/T 7714		 Xiong, Rui Sheng,Zhao, Qing Jie,Zhu, Hang Hang,et al. Synthesis of novel analogues of zanamivir as neuraminidase inhibitors[J]. CHINESE CHEMICAL LETTERS,2010,21(11):1338-1341.
APA Xiong, Rui Sheng,Zhao, Qing Jie,Zhu, Hang Hang,Liu, Zheng,Wei, Ya Bing,&Shen, Jing Shan.(2010).Synthesis of novel analogues of zanamivir as neuraminidase inhibitors.CHINESE CHEMICAL LETTERS,21(11),1338-1341.
MLA Xiong, Rui Sheng,et al."Synthesis of novel analogues of zanamivir as neuraminidase inhibitors".CHINESE CHEMICAL LETTERS 21.11(2010):1338-1341.

入库方式： OAI收割

来源：上海药物研究所

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