Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX
文献类型：期刊论文
| 作者 | Zhang, Yi1,2; Han, Zhaobin2; Li, Fuying1; Ding, Kuiling2; Zhang, Ao1
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2010 |
| 卷号 | 46期号:1页码:156-158 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/b919902k |
| 文献子类 | Article |
| 英文摘要 | The enantioselective hydrogenation of a series of challenging substrates, alpha-aryl-beta-substituted acrylic acids, was realized with high efficiency and enantioselectivity (up to 96%) under the catalysis of Ir(I) complex of Spiro-based P,N ligand, SpinPHOX. |
| WOS关键词 | ALPHA,BETA-UNSATURATED CARBOXYLIC-ACIDS ; ASYMMETRIC HYDROGENATION ; GLUCOKINASE ACTIVATORS ; DIPHOSPHINE LIGANDS ; DIABETES THERAPY ; COMPLEXES ; PSN-GK1 ; AGENTS |
| 资助项目 | NSFC[20632060] ; NSFC[20821002] ; NSFC[20620140429] ; NSFC[30772625] ; Chinese Academy of Sciences[00000000] ; Major Basic Research Development Program of China[2010CB833300] ; Science and Technology Commission of Shanghai Municipality[00000000] ; Merck Research Laboratories[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000272679200036 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279003]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Ding, Kuiling |
| 作者单位 | 1.Chinese Acad Sci, Synthet Organ & Med Chem Lab, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, State Lab Organometall Chem, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhang, Yi,Han, Zhaobin,Li, Fuying,et al. Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX[J]. CHEMICAL COMMUNICATIONS,2010,46(1):156-158. |
| APA | Zhang, Yi,Han, Zhaobin,Li, Fuying,Ding, Kuiling,&Zhang, Ao.(2010).Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX.CHEMICAL COMMUNICATIONS,46(1),156-158. |
| MLA | Zhang, Yi,et al."Highly enantioselective hydrogenation of alpha-aryl-beta-substituted acrylic acids catalyzed by Ir-SpinPHOX".CHEMICAL COMMUNICATIONS 46.1(2010):156-158. |
入库方式： OAI收割
来源：上海药物研究所
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