Determination of two metabolites of calycosin-7-O-beta-D-glucopyranoside in rat urine by HPLC
文献类型：期刊论文
| 作者 | Yang, Yan-Ling2; Xia, Guang-Xin1; Ye, Guan1 |
| 刊名 | BIOMEDICAL CHROMATOGRAPHY
 |
| 出版日期 | 2009-01 |
| 卷号 | 23期号:1页码:48-53 |
| 关键词 | HPLC calycosin-7-O-beta-D-glucopyranoside metabolite urine |
| ISSN号 | 0269-3879 |
| DOI | 10.1002/bmc.1081 |
| 文献子类 | Article |
| 英文摘要 | A simple and specific analytical method for the simultaneous determination of the two metabolites of calycosin7-O-beta-D-glucopyranoside, calycosin-7-O-beta-D-glucuronic acid methyl ester (M-1) and calycosin (M-2), in rat urine was developed using high-performance liquid chromatography. Quercetin was employed as an internal standard. The correlation coefficients of the calibration curves were higher than 0.999; both intra- and inter-day precisions of two metabolites were determined and their RSD did not exceed 10%. The accuracy and linear range were investigated in detail. The cumulative urinary excretions of two metabolites were measured. Copyright (c) 2008 John Wiley & Sons, Ltd. |
| WOS关键词 | ASTRAGALUS-MONGHOLICUS ; RETICULOENDOTHELIAL SYSTEM ; ISOFLAVONOIDS ; ROOT |
| 资助项目 | Ministry of Science and Technology of China[00000000] ; National Natural Science Foundation of China[30500655] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000262191600005 |
| 出版者 | JOHN WILEY & SONS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279351]  |
| 专题 | 药物化学研究室 上海中药现代化研究中心 |
| 通讯作者 | Yang, Yan-Ling |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China 2.Yanan Univ, Coll Med, Dept Physiol, Yanan 716000, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yang, Yan-Ling,Xia, Guang-Xin,Ye, Guan. Determination of two metabolites of calycosin-7-O-beta-D-glucopyranoside in rat urine by HPLC[J]. BIOMEDICAL CHROMATOGRAPHY,2009,23(1):48-53. |
| APA | Yang, Yan-Ling,Xia, Guang-Xin,&Ye, Guan.(2009).Determination of two metabolites of calycosin-7-O-beta-D-glucopyranoside in rat urine by HPLC.BIOMEDICAL CHROMATOGRAPHY,23(1),48-53. |
| MLA | Yang, Yan-Ling,et al."Determination of two metabolites of calycosin-7-O-beta-D-glucopyranoside in rat urine by HPLC".BIOMEDICAL CHROMATOGRAPHY 23.1(2009):48-53. |
入库方式： OAI收割
来源：上海药物研究所
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