Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases
文献类型：期刊论文
| 作者 | Liu, Yu-Ting1,4; Lin, Ze-Min2,4; He, Shi-Jun1,4 ; Zuo, Jian-Ping1,3,4
|
| 刊名 | Life sciences
 |
| 出版日期 | 2018-12-20 |
| ISSN号 | 1879-0631 |
| DOI | 10.1016/j.lfs.2018.12.033 |
| 文献子类 | Article;Review |
| 英文摘要 | Heme oxygenase-1 (HO-1), a cellular stress protein, serves a vital metabolic function as the rate-limiting enzyme in the degradation of heme to generate carbon monoxide (CO), iron, and biliverdin (BR). HO-1 may function as one of the most momentous factors of cell adaptation to oxidase stress, as well as a regulator of inflammatory signaling programs through the generation of its biologically active end products. Intensive investigation is now focusing on the potential function of HO-1 in inflammatory disorders, among which rheumatic diseases are one of the principal issues. |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266777]  |
| 专题 | 新药研究国家重点实验室 药理学第一研究室 |
| 通讯作者 | He, Shi-Jun; Zuo, Jian-Ping |
| 作者单位 | 1.University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China; 2.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China; 3.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China 4.Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China; |
| 推荐引用方式 GB/T 7714 | Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,et al. Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases[J]. Life sciences,2018. |
| APA | Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,&Zuo, Jian-Ping.(2018).Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases.Life sciences. |
| MLA | Liu, Yu-Ting,et al."Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases".Life sciences (2018). |
入库方式： OAI收割
来源：上海药物研究所
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