Heat shock protein 90: novel target for cancer therapy
文献类型：会议论文
| 作者 | Chen, Yi ; Ding, Jian
|
| 出版日期 | 2004-08 |
| 卷号 | 23 |
| 期号 | 8 |
| 页码 | 968-74 |
| 英文摘要 | The molecular chaperone heat shock protein 90 (Hsp90) is important in maintaining the conformation, stability, and function of many proteins involved in cell surviving. Hsp90 is of interest as an anticancer drug target because of its importance in maintaining the function of key oncogenic client proteins. Hsp90 inhibitors also have shown promising antitumor activity in vitro and in vivo preclinical model systems. One Hsp90 inhibitor, 17-allylamio-17- desmethoxygeldanamycin (17-AAG), is currently in clinical trial. |
| 会议录 | Ai zheng = Aizheng = Chinese journal of cancer
 |
| 文献子类 | Meeting Abstract;Article;Review |
| 语种 | 中文 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/266951]  |
| 专题 | 药理学第一研究室 |
| 作者单位 | Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai, 201203, PR China |
| 推荐引用方式 GB/T 7714 | Chen, Yi,Ding, Jian. Heat shock protein 90: novel target for cancer therapy[C]. 见:. |
入库方式： OAI收割
来源：上海药物研究所
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