Induced anoikis of gastric cancer cell lines by proanhocyanidin derived from seed of Vitis vinifera L.
文献类型：期刊论文
| 作者 | Li Ying2; Yao Libo2; Han Jiong2; Wang Lifeng2; Han Yueheng2; Liu Xinping2; Liu Shuxin3; Yu Qiang1
|
| 刊名 | Chinese Pharmacological Bulletin
 |
| 出版日期 | 2004 |
| 卷号 | 20期号:7页码:761-764 |
| ISSN号 | 1001-1978 |
| 关键词 | proanthocyanidin anoikis gastric caner cells |
| 其他题名 | 葡萄籽提取物原花青素诱导胃癌细胞脱落凋亡 |
| 文献子类 | Article |
| 英文摘要 | Aim To investigate the inductive effect of proanthocyanidin derived from seed of Vitis vinifera L on anoikis of gastric cancer cells. Methods Cell mor-phology observation, Annxin-V and PI staining assay and flow cytometry (FCM) assay were used to study the inductive effect of proanthocyanidin on cell growth condition, cell cycle changes and anoikis rate of the gastric cancer cells cultured in suspension. Results Proanthocyanidin (0. 1 mmol ? L-1) could inhibite the gastric cancer cells resistant to anoikis from forming cluster. Proanthocyanidin(0.5 mmol ? L-1) could ar-rest the different suspended gastric cancer cells in dif-ferent cell cycles and induce the gastric cancer cells to anoikis. Conclusion Resveratrol can induce anoikis of gastric cancer cells. |
| 资助项目 | 国家自然科学基金资助项目[00000000] ; 军队"十五"科研基金重点项目[00000000] |
| WOS研究方向 | General & Internal Medicine ; Oncology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1696537 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268377]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Yu Qiang |
| 作者单位 | 1.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. 2.Dept of Biochemistry and Molecular Biology, Xian, Shanxi 710032, China.; 3.Dept ofPathophysiology ,the Fourth Military Medical University, Xian, Shanxi 710032, China.; |
| 推荐引用方式 GB/T 7714 | Li Ying,Yao Libo,Han Jiong,et al. Induced anoikis of gastric cancer cell lines by proanhocyanidin derived from seed of Vitis vinifera L.[J]. Chinese Pharmacological Bulletin,2004,20(7):761-764. |
| APA | Li Ying.,Yao Libo.,Han Jiong.,Wang Lifeng.,Han Yueheng.,...&Yu Qiang.(2004).Induced anoikis of gastric cancer cell lines by proanhocyanidin derived from seed of Vitis vinifera L..Chinese Pharmacological Bulletin,20(7),761-764. |
| MLA | Li Ying,et al."Induced anoikis of gastric cancer cell lines by proanhocyanidin derived from seed of Vitis vinifera L.".Chinese Pharmacological Bulletin 20.7(2004):761-764. |
入库方式： OAI收割
来源：上海药物研究所
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